Siganos D S, Popescu C N, Siganos C S, Pistola G
Vlemma Eye Institute, Athens, Greece.
J Cataract Refract Surg. 2000 Nov;26(11):1585-9. doi: 10.1016/s0886-3350(00)00648-9.
To evaluate the effect of spherical and astigmatic excimer laser photorefractive keratectomy (PRK and PARK, respectively) on tear secretion.
The Vlemma Eye Center, Athens, Greece.
Forty-eight eyes of 48 patients had PRK (28 eyes) or PARK (20 eyes) for the correction of myopia and combined myopic astigmatism. The fellow eye served as a control. The mean preoperative spherical equivalent was -3.96 diopters (D) +/- 1.00 (SD) in the PRK eyes (range -2.00 to -6.50 D) and -3.45 +/- 0.50 D in the PARK eyes (range -1.75 to -6.00 D). Attempted correction aimed at emmetropia. Schirmer I and II and tear film breakup time (BUT) tests were performed preoperatively and 1, 3, and 6 months postoperatively. All tests were correlated to the amount of attempted correction.
In the PRK group, the preoperative mean values were Schirmer I, 16.20 mm; Schirmer II, 12.73 mm; and BUT, 16.46 sec. At 1 month, they were 12.23 mm, 8.46 mm, and 13.33 sec, respectively; at 3 months, 13.86 mm, 10.64 mm, and 14.42 sec, respectively; at 6 months, 14.32 mm, 11.32 mm, and 15.36 sec, respectively. In the PARK group, the mean Schirmer I, II, and BUT values were preoperatively 18.52 mm, 14.86 mm, and 17.42 sec, respectively; at 1 month, 14.5 mm, 10.4 mm, and 14.36 sec, respectively; at 3 months, 15.36 mm, 11.81 mm, and 14.72 sec, respectively; and at 6 months, 16.5 mm, 12.15 mm, 16.5 sec, respectively. No correlation to the amount of attempted correction was found. Fellow-eye tests were not affected at any interval.
In the first 6 months after PRK and PARK, tear secretion test values decreased.
评估球面和散光准分子激光屈光性角膜切削术（分别为PRK和PARK）对泪液分泌的影响。
希腊雅典的Vlemma眼科中心。
48例患者的48只眼接受了PRK（28只眼）或PARK（20只眼）手术，以矫正近视及合并的近视散光。对侧眼作为对照。PRK组术前平均等效球镜度为-3.96屈光度（D）±1.00（标准差）（范围为-2.00至-6.50 D），PARK组为-3.45±0.50 D（范围为-1.75至-6.00 D）。目标矫正为正视。术前及术后1、3和6个月进行Schirmer I和II试验以及泪膜破裂时间（BUT）测试。所有测试均与目标矫正量相关。
PRK组术前平均值为Schirmer I 16.20 mm、Schirmer II 12.73 mm、BUT 16.46秒。1个月时，分别为12.23 mm、8.46 mm和13.33秒；3个月时，分别为13.86 mm、10.64 mm和14.42秒；6个月时，分别为14.32 mm、11.32 mm和15.36秒。PARK组术前Schirmer I、II和BUT的平均值分别为18.52 mm、14.86 mm和17.42秒；1个月时，分别为14.5 mm、10.4 mm和14.36秒；3个月时，分别为15.36 mm、11.81 mm和14.72秒；6个月时，分别为16.5 mm、12.15 mm、16.5秒。未发现与目标矫正量相关。对侧眼测试在任何时间段均未受影响。
PRK和PARK术后的前6个月，泪液分泌测试值下降。
