Le Bouëdec G, Rabishong B, Canis M, Achard J L, Pomel C, Dauplat J
Centre Régional de Lutte Contre le Cancer Jean Perrin, 58, rue Montalembert, B.P. 392, 63011 Clermont-Ferrand Cedex.
J Gynecol Obstet Biol Reprod (Paris). 2000 Oct;29(6):564-70.
To evaluate the place of ovarian transposition by laparoscopy in an effort to preserve ovarian function without compromising oncological safety among young women requiring intravaginal brachytherapy before surgery for cervical cancer.
The series was represented by 20 cases, all FIGO stage I squamous cell malignant diseases of the cervix. Mean age: 32 years (range 23-40). Oophoropexy (7 instances) or lateral high ovarian transposition (13 instances) was performed by laparoscopy, just before brachytherapy using cesium 137.
Continued hormonal function was achieved in 58% of the available cases, 50% (3/6) after oophoropexy, 68% (8/11) after ovarian transposition. Mean follow-up was 8.5 years (range 5-13). The mean radiation dose absorbed by the displaced ovary was 2.6 Gy (range 1. 2-5.9).
Ovarian transposition through laparoscopy before brachytherapy should be advised for selected stage I squamous type malignant tumor size 2 cm without lymphatic/vascular channel invasion by neoplastic emboli and without lymph node involvement. This procedure has been abandoned in our institution, instead of this, primary surgical treatment is accomplished (laparoscopically-assisted vaginal) radical hysterectomy is associated with orthotopic ovarian conservation.
评估腹腔镜下卵巢移位术在宫颈癌手术前行阴道近距离放疗的年轻女性中保留卵巢功能而不影响肿瘤学安全性方面的作用。
该系列包括20例患者,均为FIGO I期宫颈鳞状细胞恶性疾病。平均年龄:32岁(范围23 - 40岁)。在使用铯137进行近距离放疗前,通过腹腔镜进行卵巢固定术(7例)或高位卵巢侧方移位术(13例)。
在可评估的病例中,58%实现了持续的激素功能,卵巢固定术后为50%(3/6),卵巢移位术后为68%(8/11)。平均随访8.5年(范围5 - 13年)。移位卵巢吸收的平均辐射剂量为2.6 Gy(范围1.2 - 5.9)。
对于选定的I期鳞状型恶性肿瘤,肿瘤大小2 cm,无淋巴/血管通道受肿瘤栓子侵犯且无淋巴结受累的患者,建议在近距离放疗前通过腹腔镜进行卵巢移位术。本机构已放弃该手术,取而代之的是进行一期手术治疗(腹腔镜辅助阴道)根治性子宫切除术并原位保留卵巢。