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[利用医学能力网络进行生长和身体发育障碍早期检测及优化治疗的模型方案]

[Model program for the early detection and optimal treatment of disorders of growth and physical development using a medical competence netwok].

作者信息

Keller E, Burmeister J, Gausche R, Keller A, Hermanussen M, Kiess W

机构信息

Universitätskinderklinik Leipzig.

出版信息

Z Arztl Fortbild Qualitatssich. 2000 Sep;94(8):695-8.

Abstract

The growth and development of a child is a mirror of his living conditions and health. For decades pediatricians have been trying to achieve an earlier identification of children with growth disorders. The measures of prevention in Germany have not been successful so far. Diagnosis for example of GH-deficiency to ensure optimal substitution with growth hormone is usually not early enough. A screening system using an auxological data bank for growth disorders has been set up by us recently. Since 1998 we have collected height and weight measurements in relation to age and sex from patients cared for by a large number of pediatricians in the region of Leipzig, Germany. By september 1999, 30,182 children of different ages have been screened. The system identifies children with short stature below the 3. centile and tall stature above the 97. centile of the German Synthetic Normcurve (Hermanussen/Burmeister 1999). In 6.81% of the children a growth disorder was identified (3.03% above 97. and 3.78% below 3. centile). In 54 cases (0.18%) we found a pathological reason for short or tall stature. A sensitive screening system has been set up for the early detection of growth disorders and obesity in childhood. We generate a data pool for multiple questions in research of human growth. We will generate yearly reports for the development of new strategies in preventive medicine.

摘要

儿童的生长发育是其生活条件和健康状况的反映。几十年来,儿科医生一直致力于更早地识别出生长发育障碍的儿童。到目前为止,德国的预防措施尚未取得成功。例如,生长激素缺乏症的诊断通常不够早,无法确保用生长激素进行最佳替代治疗。我们最近建立了一个利用人体测量数据库来筛查生长发育障碍的系统。自1998年以来,我们收集了德国莱比锡地区众多儿科医生所诊治患者的身高和体重数据,这些数据与年龄和性别相关。到1999年9月,已对30182名不同年龄段的儿童进行了筛查。该系统能识别出身高低于德国综合标准曲线第3百分位数的身材矮小儿童以及高于第97百分位数的身材高大儿童(赫尔曼努森/布尔迈斯特,1999年)。在6.81%的儿童中发现了生长发育障碍(3.03%高于第97百分位数,3.78%低于第3百分位数)。在54例(0.18%)中,我们发现了身材矮小或高大的病理原因。已建立了一个敏感的筛查系统,用于早期发现儿童期的生长发育障碍和肥胖症。我们为人类生长研究中的多个问题生成了一个数据库。我们将每年发布报告,以制定预防医学的新策略。

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