Palikhova T A
Department of Psychophysiology, Lomonosov State University, Moscow.
Zh Vyssh Nerv Deiat Im I P Pavlova. 2000 Sep-Oct;50(5):775-90.
The synaptic plasticity is a background for learning and memory. Identifiable synapses that are the synapses between individually identifiable neurons are a very convenient model for studying plasticity. Synapses between the interoceptive mechanosensory neurons and the command neurons of the withdrawal behavior were identified in the Helix lucorum brain. It was shown that synaptic plasticity estimated by the dynamics of the elementary postsynaptic potentials elicited by single presynaptic spikes differed from the synaptic plasticity estimated by the dynamics of compound synaptic responses of the same neurons to sensory stimulation. Habituation and heterosynaptic facilitation phenomena are discussed in terms of the dynamics of the elementary postsynaptic potentials.
突触可塑性是学习和记忆的基础。可识别的突触，即单个可识别神经元之间的突触，是研究可塑性的非常便利的模型。在福寿螺脑内已识别出感受性机械感觉神经元与退缩行为的指令神经元之间的突触。结果表明，由单个突触前峰电位引发的微小突触后电位的动力学所估计的突触可塑性，与同一神经元对感觉刺激的复合突触反应的动力学所估计的突触可塑性不同。根据微小突触后电位的动力学对习惯化和异突触易化现象进行了讨论。
