孕早期胎儿长骨长度的估计：数学公式之间的比较
[Estimate of fetal long bone length in early pregnancy: comparison between mathematical formulae].
作者信息
Rosati P, Guariglia L
机构信息
Istituto di Clinica Ostetrica e Ginecologica, Università Cattolica del Sacro Cuore, Roma.
出版信息
Minerva Ginecol. 2000 Jun;52(6):229-33.
BACKGROUND
The aim of this study was to determine the efficacy of different mathematical formulae described in the literature and to propose new mathematical formulae to estimate fetal long bones biometry in early pregnancy.
METHODS
In 1481 singleton euploid fetuses a transvaginal ultrasound examination was performed between 9 and 16 week's gestation. To determine the relationship between the biparietal diameter and long bone lengths, a sample group of 100 randomly chosen normal fetuses was evaluated by regression equations. The equations derived were then tested in the remaining 1381 control fetuses and the mean absolute percentage error and the mean systematic error with their standard deviations were compared with previously reported mathematical formulae by other authors.
RESULTS
All previous formulae described in literature when applied to our population revealed an overestimation of expected long bones measurements. Using our mathematical formulae, the mean absolute percentage error and the mean systematic error were 11.5% and 1% in estimating femur and 10.9% and 0.8% in estimating humerus length, respectively.
CONCLUSIONS
These newly derived ultrasound morphometric formulae could be proposed as reliable models in estimating fetal long bone lengths in early pregnancy.
背景
本研究的目的是确定文献中描述的不同数学公式的有效性，并提出新的数学公式来估计孕早期胎儿长骨的生物测量值。
方法
对1481名单胎整倍体胎儿在妊娠9至16周期间进行经阴道超声检查。为了确定双顶径与长骨长度之间的关系，通过回归方程对100例随机选择的正常胎儿样本组进行评估。然后在其余1381例对照胎儿中测试得出的方程，并将平均绝对百分比误差和平均系统误差及其标准差与其他作者先前报道的数学公式进行比较。
结果
文献中描述的所有先前公式应用于我们的人群时，均显示出对预期长骨测量值的高估。使用我们的数学公式，估计股骨时平均绝对百分比误差和平均系统误差分别为11.5%和1%，估计肱骨长度时分别为10.9%和0.8%。
结论
这些新推导的超声形态测量公式可作为估计孕早期胎儿长骨长度的可靠模型。
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