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吉兰-巴雷综合征

Guillain-Barré syndrome.

作者信息

Seneviratne U

机构信息

Institute of Neurology, National Hospital of Sri Lanka, Colombo 8, Sri Lanka.

出版信息

Postgrad Med J. 2000 Dec;76(902):774-82. doi: 10.1136/pmj.76.902.774.

Abstract

Guillain-Barré syndrome is an autoimmune disorder encompassing a heterogeneous group of pathological and clinical entities. Antecedent infections are thought to trigger an immune response, which subsequently cross reacts with nerves leading to demyelination or axonal degeneration. Both intravenous immunoglobulin treatment and plasma exchange have been found to be equally beneficial. Several factors are useful in predicting the outcome of these patients.

摘要

吉兰-巴雷综合征是一种自身免疫性疾病,涵盖了一组病理和临床特征各异的病症。前驱感染被认为会引发免疫反应,随后该反应会与神经发生交叉反应,导致脱髓鞘或轴突变性。静脉注射免疫球蛋白治疗和血浆置换已被证明具有同等疗效。有几个因素有助于预测这些患者的预后。

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