Aygul Recep, Deniz Orhan, Guzelcik Metin, Kotan Dilcan
Department of Neurology, Faculty of Medicine, Ataturk University, Erzurum, Turkey.
Eurasian J Med. 2010 Dec;42(3):157-9. doi: 10.5152/eajm.2010.43.
It has been reported that approximately two thirds of patients diagnosed with Guillain-Barré syndrome (GBS) have had a prodromal illness within a four-week period preceding the onset of GBS. This prodromal illness is most commonly an upper respiratory tract illness or, secondly, gastroenteritis. However, specific infectious agents, such as mycoplasma, cytomegalovirus, Ebstein-Barr virus, vaccinia, variola, campylobacter, varicella-zoster, measles, mumps, hepatitis A and B viruses, rubella, influenza A and B viruses, coxackie and echoviruses, have also been reported to be certain or probable etiologic antecedent agents of GBS. In contrast, GBS during active brucellosis has rarely been reported. This article presents the case of a 28 year-old male patient with GBS during active brucellosis who responded fully to treatment directed to brucellosis. and it is stressed that brucellosis should be considered as a probable etiologic agent in patients with GBS who live in areas where brucellosis is endemic.
据报道,约三分之二被诊断为吉兰 - 巴雷综合征(GBS)的患者在GBS发病前四周内曾患前驱疾病。这种前驱疾病最常见的是上呼吸道疾病,其次是肠胃炎。然而,特定的感染因子,如支原体、巨细胞病毒、EB病毒、牛痘、天花、弯曲杆菌、水痘 - 带状疱疹病毒、麻疹、腮腺炎、甲型和乙型肝炎病毒、风疹、甲型和乙型流感病毒、柯萨奇病毒和埃可病毒,也被报道为GBS确定或可能的病因前体。相比之下,活动性布鲁氏菌病期间发生GBS的情况很少被报道。本文介绍了一名28岁男性患者,在活动性布鲁氏菌病期间患GBS,对针对布鲁氏菌病的治疗有完全反应。并强调,在布鲁氏菌病流行地区患有GBS的患者中,应将布鲁氏菌病视为可能的病因。