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普通人群中与创伤后应激障碍相关的睡眠障碍和精神疾病。

Sleep disturbances and psychiatric disorders associated with posttraumatic stress disorder in the general population.

作者信息

Ohayon M M, Shapiro C M

机构信息

Sleep Disorders Center, Stanford University School of Medicine, CA 94305, USA.

出版信息

Compr Psychiatry. 2000 Nov-Dec;41(6):469-78. doi: 10.1053/comp.2000.16568.

DOI:10.1053/comp.2000.16568
PMID:11086154
Abstract

The aim of the study was to assess sleep disturbances in subjects with posttraumatic stress disorder (PTSD) from an urban general population and to identify associated psychiatric disorders in these subjects. The study was performed with a representative sample of 1,832 respondents aged 15 to 90 years living in the Metropolitan Toronto area who were surveyed by telephone (participation rate, 72.8%). Interviewers used Sleep-EVAL, an expert system specifically designed to conduct epidemiologic studies of sleep and mental disorders in the general population. Overall, 11.6% of the sample reported having experienced a traumatic event, with no difference in the proportion of men and women. Approximately 2% (1.8%) of the entire sample were diagnosed by the system as having PTSD at the time of interview. The rate was higher for women (2.6%) than for men (0.9%), which translated into an odds ratio (OR) of 2.8 (95% confidence interval [CI], 1.3 to 6.1). PTSD was strongly associated with other mental disorders: 75.7% of respondents with PTSD received at least one other diagnosis. Most concurrent disorders (80.7%) appeared after exposure to the traumatic event. Sleep disturbances also affected about 70% of the PTSD subjects. Violent or injurious behaviors during sleep, sleep paralysis, sleep talking, and hypnagogic and hypnopompic hallucinations were more frequently reported in respondents with PTSD. Considering the relatively high prevalence of PTSD and its important comorbidity with other sleep and psychiatric disorders, an assessment of the history of traumatic events should be part of a clinician's routine inquiry in order to limit chronicity and maladjustment following a traumatic exposure. Moreover, complaints of rapid eye movement (REM)-related sleep symptoms could be an indication of an underlying problem stemming from PTSD.

摘要

本研究的目的是评估来自城市普通人群的创伤后应激障碍(PTSD)患者的睡眠障碍情况,并确定这些患者中相关的精神障碍。该研究对居住在大多伦多地区的1832名年龄在15至90岁的受访者进行了电话调查(参与率为72.8%),选取了具有代表性的样本。访谈者使用了Sleep-EVAL,这是一个专门设计用于对普通人群的睡眠和精神障碍进行流行病学研究的专家系统。总体而言,11.6%的样本报告曾经历过创伤事件,男性和女性的比例没有差异。在访谈时,整个样本中约2%(1.8%)被该系统诊断为患有PTSD。女性的患病率(2.6%)高于男性(0.9%),这转化为优势比(OR)为2.8(95%置信区间[CI],1.3至6.1)。PTSD与其他精神障碍密切相关:75.7%的PTSD受访者至少接受过一项其他诊断。大多数并发疾病(80.7%)在接触创伤事件后出现。睡眠障碍也影响了约70%的PTSD患者。PTSD患者更频繁地报告睡眠中的暴力或伤害行为、睡眠麻痹、说梦话以及入睡和觉醒幻觉。鉴于PTSD的患病率相对较高,且与其他睡眠和精神障碍有重要的共病情况,临床医生在常规问诊中应询问创伤事件史,以减少创伤暴露后的慢性化和适应不良。此外,对快速眼动(REM)相关睡眠症状的主诉可能表明存在源于PTSD的潜在问题。

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