Martínez B, Gómez J, Guerra B, Gómez Vargas B, Gómez J R, Siamarro E, Canteras M, Valdes M
Servicio de Medicina Interna-Infecciosas, Hospital Universitario Virgen de la Arrixaca, Murcia.
Rev Esp Quimioter. 2000 Sep;13(3):276-80.
Urinary infections due to gram-negative bacteria are important because of their high frequency, morbidity and mortality. In order to evaluate the risk factors and prognostics a group of 50 patients with nosocomial urinary infections were studied prospectively and consecutively and were compared with another group of 50 patients with similar characteristics but no infection. The most isolated bacteria were Escherichia coli (68%), followed by Pseudomonas aeruginosa (20%). Bacteremia was found in 22% of the cases. Risk factors included female gender, medical services, nosocomial acquisition, previous use of manipulation techniques such as vesicular probe, prior urinary infections, and the use of cytostatic drugs in the previous six weeks. Mortality was 4%. The factors significantly associated with a poor prognosis were the following: severe underlying disease, a clinically critical situation, previous surgery, complications, type of gram-negative bacteria, use of third generation cephalosporins and ciprofloxacin in the previous six weeks and older age. The mortality of the control group was 8%.