Verrotti A, Morresi S, Basciani F, Cutarella R, Morgese G, Chiarelli F
Department of Medicine, University of Chieti, Ospedale Policlinico, Italy.
Neurology. 2000 Nov 14;55(9):1393-5. doi: 10.1212/wnl.55.9.1393.
To evaluate when it is possible to discontinue anticonvulsant treatment in children with cryptogenic partial epilepsy, the authors studied 89 epileptic children divided into two groups: Group A, 45 children whose therapy was discontinued after 1 year from the last seizure; and Group B, 44 children whose therapy was stopped after 2 years from the last seizure. After 5 years of follow-up, the recurrence rate was similar in the two groups of patients (Group A, 28.8%; Group B, 25%). It is safe to discontinue the anticonvulsant therapy in children with cryptogenic partial epilepsy who were seizure free for only 1 year.
为评估隐源性部分性癫痫患儿何时可以停用抗惊厥治疗，作者对89例癫痫患儿进行了研究，将其分为两组：A组，45例患儿在最后一次发作后1年停止治疗；B组，44例患儿在最后一次发作后2年停止治疗。经过5年的随访，两组患者的复发率相似（A组为28.8%；B组为25%）。对于仅1年无发作的隐源性部分性癫痫患儿，停用抗惊厥治疗是安全的。
