Pavlović S
Klinika za ocne bolesti, Justus-Liebig-Univerzitet, Giessen.
Med Pregl. 2000 May-Jun;53(5-6):257-61.
Cataract extraction in children has improved and became more popular over the past few decades but, due to particular features of children's eyes, still remains controversial--especially regarding the intraocular lens implantation.
In contrast to adults, indications for cataract surgery in children are much more difficult to determine. Since subjective visual acuity cannot be obtained, greater reliance must be placed on the morphology and location of the lens opacity, and the behavior of the child. Forced preferential looking and visual evoked potentials can be helpful, but they should not be the only criteria.
In management of pediatric cataract, correction of postoperative aphakia is still an incompletely resolved problem. Conventionally, optical correction is achieved by spectacles or contact lenses. The power of both spectacles and contact lenses can be readily adjusted to compensate for ocular growth. The success of both depends significantly on parental compliance and the child's acceptance. Hutchinson reported that 44% children with aphakia stopped wearing glasses or contact lenses 2 months after surgery. Contact lens wearing can also result in a number of corneal complications, including infectious keratitis, corneal vascularization and hypoxic corneal ulceration. IOL implantation is theoretically superior to glasses and contact lenses since it provides almost immediate optical correction which is much more reliable because it does not depend on parental or child's compliance. Still, there are many controversies about IOL implantation in infants and young children like IOL-size, material, IOL power calculation, prevention and management of secondary cataract, as well as long term safety of IOLs in children's eyes. Although short-term anatomic results after cataract extraction and primary IOL implantation in children are excellent and stable, long-term follow-up is necessary to answer questions about the long-term safety of implants in children's eyes.
A higher incidence of postoperative inflammation and opacification of the optical axis has been reported after pediatric cataract surgery. Posterior capsular opacification is almost an unavoidable complication in children's eyes if the posterior capsule is left intact. Several methods have been proposed in order to keep the optical axis clear in infants and young children. Comparison of posterior capsulectomy with and without anterior vitrectomy showed that posterior capsular opacification rates are diminished only after combined posterior capsulectomy and anterior vitrectomy and not after capsulectomy alone. Posterior capsulorhexis with optic capture seems to effectively prevent posterior capsular opacification. This technique eliminates the need for anterior vitrectomy and ensures the centration of the intraocular lens. Glaucoma and retinal detachment are late complications of pediatric cataract surgery. On average glaucoma develops 6.8 years after cataract operation. Retinal detachment develops several decades after cataract extraction.
The functional results after pediatric cataract surgery depend not only on the anatomic success of the operation and postoperative maintenance of a clear optical axis, but even more on aphakic visual rehabilitation. Children's eyes with cataract severe enough to require cataract extraction usually have some degree of amblyopia already present prior to surgery. In unilateral pseudophakia amblyopia develops postoperatively unless the fellow eye is occluded or optically and/or pharmacologically penalized. Immediate optical correction is desirable because prevention and/or therapy of amblyopia should be initiated directly after surgery. Parental compliance with occlusion therapy and not successful surgery are major determinants of a good visual outcome in unilateral aphakic/pseudophakic children.
在过去几十年中,儿童白内障摘除术已有所改进且变得更为普遍,但由于儿童眼睛的特殊特征,该手术仍存在争议——尤其是在人工晶状体植入方面。
与成人不同,儿童白内障手术的指征更难确定。由于无法获得主观视力,必须更多地依赖晶状体混浊的形态和位置以及儿童的行为。强迫优先注视和视觉诱发电位可能会有所帮助,但它们不应是唯一的标准。
在小儿白内障的治疗中,术后无晶状体的矫正仍是一个尚未完全解决的问题。传统上,光学矫正通过眼镜或隐形眼镜来实现。眼镜和隐形眼镜的度数都可以很容易地调整以补偿眼球的生长。两者的成功都很大程度上取决于家长的配合程度和孩子的接受程度。哈钦森报告称,44% 的无晶状体儿童在术后2个月就不再佩戴眼镜或隐形眼镜。佩戴隐形眼镜还可能导致一些角膜并发症,包括感染性角膜炎、角膜血管化和缺氧性角膜溃疡。理论上,人工晶状体植入优于眼镜和隐形眼镜,因为它几乎能立即提供光学矫正,而且更可靠,因为它不依赖于家长或孩子的配合。然而,对于婴幼儿人工晶状体植入仍存在许多争议,如人工晶状体的尺寸、材料、人工晶状体度数计算、后发性白内障的预防和处理,以及人工晶状体在儿童眼中的长期安全性。尽管儿童白内障摘除联合一期人工晶状体植入术后的短期解剖学效果良好且稳定,但仍需要长期随访来解答人工晶状体在儿童眼中长期安全性的问题。
据报道,小儿白内障手术后炎症和视轴混浊的发生率较高。如果后囊膜保持完整,后囊膜混浊在儿童眼中几乎是不可避免的并发症。为了保持婴幼儿视轴清晰,已经提出了几种方法。对有或无前部玻璃体切除术的后囊膜切开术进行比较表明,只有在后囊膜切开术联合前部玻璃体切除术后,后囊膜混浊率才会降低,单独的囊膜切开术则不会。带光学部撕囊似乎能有效预防后囊膜混浊。该技术无需前部玻璃体切除术,并能确保人工晶状体居中。青光眼和视网膜脱离是小儿白内障手术的晚期并发症。平均而言,青光眼在白内障手术后6.8年发生。视网膜脱离在白内障摘除术后几十年发生。
小儿白内障手术后的功能结果不仅取决于手术的解剖学成功以及术后视轴的清晰维持,更取决于无晶状体眼的视觉康复。患有严重到需要进行白内障摘除的白内障的儿童眼睛,在手术前通常已经存在一定程度的弱视。在单侧人工晶状体眼,除非对侧眼被遮盖或进行光学和/或药物性抑制,否则术后会发生弱视。理想的是立即进行光学矫正,因为弱视的预防和/或治疗应在手术后直接开始。家长对遮盖疗法的配合程度而非手术的成功与否,是单侧无晶状体/人工晶状体眼儿童良好视觉结果的主要决定因素。