Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea.
Acta Ophthalmol. 2012 May;90(3):231-6. doi: 10.1111/j.1755-3768.2010.01872.x. Epub 2010 Sep 2.
To evaluate the long-term visual outcome after early surgery of bilateral dense congenital cataracts, aphakic correction with glasses and secondary intraocular lens (IOL) implantation around 2 years of age.
The medical records of paediatric patients who underwent cataract extraction, aphakic correction and secondary IOL implantation from 1993 to 2004 at Seoul National University Children's Hospital were reviewed retrospectively. Age at secondary IOL implantation, axial length (AL), best corrected visual acuity (BCVA), refractive error, ocular alignment, stereopsis, and postoperative ocular complications were recorded.
Thirty-seven paediatric bilateral pseudophakic patients were identified with a mean follow-up period of 81.4 months. Best corrected visual acuity of 20/40 or better were attained in 44.0% of eyes, and the median BCVA was 20/50. Preoperative factors associated with poor visual prognosis included cataract surgery after 8 weeks of age, interocular AL difference of 0.5 mm or more, and glaucoma. Amblyopic eyes showed more myopic change compared to fellow eyes. Good or moderate binocular function was achieved in 18.9% of all patients. Incidences of strabismus, glaucoma, posterior capsular opacity formation were 46.0%, 32.4% and 4.0%, respectively.
Good postoperative BCVA and binocular function were achieved in most healthy children with bilateral dense congenital cataract and no posterior segment pathology. Early cataract surgery, aphakic correction with glasses and secondary IOL implantation around 2 years of age appears to be appropriate methods.
评估双侧致密性先天性白内障早期手术、无晶状体眼矫正及 2 岁左右二期人工晶状体(IOL)植入后的长期视力结果。
回顾性分析 1993 年至 2004 年期间在首尔国立大学儿童医院行白内障摘除、无晶状体眼矫正及二期 IOL 植入术的儿科患者的病历。记录二期 IOL 植入的年龄、眼轴长度(AL)、最佳矫正视力(BCVA)、屈光不正、眼球运动、立体视和术后眼部并发症。
确定了 37 名双侧假性晶状体患儿,平均随访时间为 81.4 个月。44.0%的眼视力达到 20/40 或更好,中位 BCVA 为 20/50。与较差的视力预后相关的术前因素包括 8 周龄后行白内障手术、眼间 AL 差异 0.5mm 或以上和青光眼。弱视眼的近视变化较对侧眼更为明显。所有患者中,良好或中度双眼功能的比例为 18.9%。斜视、青光眼、后发性白内障的发生率分别为 46.0%、32.4%和 4.0%。
对于无后部病变的健康双侧致密性先天性白内障儿童,术后 BCVA 和双眼功能良好。早期白内障手术、无晶状体眼矫正及 2 岁左右二期 IOL 植入术似乎是合适的方法。