Pavlović S U, Velimirović D, Rebić P, Baute V, Zivković M B, Stojanov P, Jelić V, Milasinović G
Pacemaker Centre, Clinical Centre of Serbia, Belgrade.
Srp Arh Celok Lek. 2000 Jul-Aug;128(7-8):229-33.
A comparison was made between metabolic parameters during exercise in patients with implanted dual sensor VVIR pacemakers. We analyzed two groups of patients with implanted dual sensor responsive pacemakers. The first group was composed of 14 patients (mean age 37.7 years) who had implanted Topaz pacemakers. The second group of 9 patients had a Legend Plus (mean age 44.7 years). A control group consisted of 54 healthy individuals (mean age 40.4 years). Testing was performed on treadmill, using a stepwise staircase loading CAEP protocol. Directly measured and mathematically calculated parameters used in assessment of metabolic impact of pacemaker function were: minute ventilation (MV), MV/body surface, MV/body mass unit, oxygen consumption, oxygen consumption/body surface, oxygen consumption/heart rate (oxygen pulse), oxygen consumption/body mass unit, carbon dioxide production, respiratory index. The majority of the observed parameters revealed no statistically significant difference between the control group and the patients with dual sensor or single sensor controlled rate response. However, oxygen pulse showed a statistically significant difference when comparing the group with single sensor controlled rate response with dual sensor controlled rate response and control group (p < 0.05). Other parameters indicating an advantage of dual sensor controlled rate were the time period of reaching anaerobic threshold (respiratory index) and exercise duration. They both displayed a statistically significant difference between dual sensor controlled rate response and single sensor rate response (p < 0.05) with no significant difference compared to control group (p > 0.05).
对植入双传感器VVIR起搏器的患者运动期间的代谢参数进行了比较。我们分析了两组植入双传感器响应式起搏器的患者。第一组由14名植入Topaz起搏器的患者组成(平均年龄37.7岁)。第二组9名患者植入了Legend Plus起搏器(平均年龄44.7岁)。对照组由54名健康个体组成(平均年龄40.4岁)。使用逐步阶梯负荷CAEP方案在跑步机上进行测试。用于评估起搏器功能代谢影响的直接测量和数学计算参数包括:分钟通气量(MV)、MV/体表面积、MV/体重单位、耗氧量、耗氧量/体表面积、耗氧量/心率(氧脉搏)、耗氧量/体重单位、二氧化碳产生量、呼吸指数。大多数观察到的参数显示,对照组与双传感器或单传感器控制心率响应的患者之间无统计学显著差异。然而,在比较单传感器控制心率响应组与双传感器控制心率响应组及对照组时,氧脉搏显示出统计学显著差异(p<0.05)。表明双传感器控制心率具有优势的其他参数是达到无氧阈值的时间段(呼吸指数)和运动持续时间。它们在双传感器控制心率响应与单传感器心率响应之间均显示出统计学显著差异(p<0.05),与对照组相比无显著差异(p>0.05)。