Matsuoka H, Mavrantonis C, Wexner S D, Oliveira L, Gilliland R, Pikarsky A
Department of Colorectal Surgery, Cleveland Clinic Florida, Fort Lauderdale 33309, USA.
Dis Colon Rectum. 2000 Nov;43(11):1561-7. doi: 10.1007/BF02236739.
Patients with idiopathic or neurogenic incontinence without an isolated sphincter defect may be suitable candidates for a postanal repair. The aim of this study was to assess the results of postanal repair in patients with idiopathic or neurogenic fecal incontinence and to evaluate the role of various parameters, including preoperative physiologic testing on outcome.
Postanal repair was offered by a single surgeon to patients meeting the following criteria: incontinence score of at least 12 of 20, absence of an isolated anterior external anal sphincter defect, and failed conservative, medical, and biofeedback management. Physiologic investigation and clinical findings of female patients who had postanal repair for fecal incontinence between 1992 and 1998 were reviewed. Physiologic investigation included anorectal manometry, pudendal nerve terminal motor latency, concentric needle electromyography, and endoanal ultrasonography. Follow-up was obtained by telephone questionnaire; moreover, patients were asked to grade the outcome of their surgery as excellent or good (success) or as fair or poor (failure).
Twenty-one patients of median age 68 (range, 40-80) years had a mean duration of fecal incontinence before postanal repair of 6.8 (range, 0.5-22) years. Twenty patients (95 percent) were available for at least one year of follow-up. Seventeen patients (80.9 percent) had at least one prior vaginal delivery, and prior sphincteroplasty had been performed in 10 patients (47.6 percent). The morbidity and mortality rates were 5 and 0 percent, respectively. After a mean follow-up period of three (range, 1-7.5) years, seven patients (35 percent) considered surgery to be successful and had a statistically significant decrease in their incontinence score. Neither prolongation of pudendal nerve terminal motor latency nor external sphincter damage as noted on electromyography or any of the preoperative manometric parameters correlated with outcome. Furthermore, patients' ages at surgery did not correlate with the degree of postoperative improvement in continence scores nor did the duration of the patients' symptoms, number of vaginal deliveries, or a history of previous surgery for fecal incontinence.
None of the factors assessed was demonstrated to be predictive of outcome after postanal repair; moreover, the currently available preoperative testing has not altered the success rate, which remains low (35 percent). Despite the low success rate, the absence of any mortality and the low morbidity suggest that postanal repair may be a valid therapeutic approach. However, it should be offered only to selected patients with persistent, severe fecal incontinence despite an anatomically intact external anal sphincter who are not candidates for or refuse all other operative modalities.
对于特发性或神经源性尿失禁且无孤立性括约肌缺陷的患者,可能适合进行肛门后修复术。本研究的目的是评估肛门后修复术治疗特发性或神经源性大便失禁患者的效果,并评估包括术前生理测试在内的各种参数对预后的作用。
由一名外科医生为符合以下标准的患者实施肛门后修复术:失禁评分为20分中的至少12分,无孤立性肛门外括约肌前部缺陷,且保守治疗、药物治疗和生物反馈治疗均失败。回顾了1992年至1998年间因大便失禁接受肛门后修复术的女性患者的生理检查和临床结果。生理检查包括肛门直肠测压、阴部神经终末运动潜伏期、同心针电极肌电图和肛门内超声检查。通过电话问卷进行随访;此外,要求患者将手术结果评为优秀或良好(成功)或一般或差(失败)。
21例患者,中位年龄68岁(范围40 - 80岁),肛门后修复术前大便失禁的平均持续时间为6.8年(范围0.5 - 22年)。20例患者(95%)获得了至少一年的随访。17例患者(80.9%)至少有一次经阴道分娩史,10例患者(47.6%)曾接受过括约肌成形术。发病率和死亡率分别为5%和0%。平均随访三年(范围1 - 7.5年)后,7例患者(35%)认为手术成功,失禁评分有统计学意义的下降。阴部神经终末运动潜伏期延长、肌电图显示的外括约肌损伤或任何术前测压参数均与预后无关。此外,患者手术时的年龄与术后控便评分的改善程度无关,患者症状持续时间、经阴道分娩次数或既往大便失禁手术史也与术后控便评分的改善程度无关。
所评估的因素均未被证明可预测肛门后修复术后的预后;此外,目前可用的术前测试并未改变成功率,成功率仍然较低(35%)。尽管成功率较低,但无任何死亡病例且发病率较低表明肛门后修复术可能是一种有效的治疗方法。然而,仅应向那些尽管肛门外括约肌解剖结构完整但仍存在持续性、严重大便失禁且不适合或拒绝所有其他手术方式的特定患者提供该手术。