麦氏棒状杆菌：一种结膜特异性病原体。
Corynebacterium macginleyi: a conjunctiva specific pathogen.
作者信息
Joussen A M, Funke G, Joussen F, Herbertz G
机构信息
Department of Ophthalmology, Technical University of Aachen (RWTH), Aachen, Germany.
出版信息
Br J Ophthalmol. 2000 Dec;84(12):1420-2. doi: 10.1136/bjo.84.12.1420.
Abstract
BACKGROUND
Although non-diphtherial corynebacteria are ubiquitous in nature and commonly colonise the skin and mucous membranes of humans, they rarely account for clinical infection.
METHODS AND RESULTS
10 patients with unilateral conjunctivitis are described in which Corynebacterium macginleyi was isolated. This species has only recently been reported to be exclusively isolated form ocular surfaces. C macginleyi was uniformly susceptible to topical antibiotics commonly used in ophthalmology.
CONCLUSION
Despite the fact that the pathogenicity of C macginleyi is not yet assured, this micro-organism should be recognised as a potential cause of bacterial superinfections. Appropriate antibiotic therapy leads to its elimination and resolution of the conjunctivitis.
摘要
背景
尽管非白喉棒状杆菌在自然界中普遍存在，且通常定植于人类的皮肤和黏膜，但它们很少导致临床感染。
方法与结果
本文描述了10例单侧结膜炎患者，从中分离出了麦氏棒状杆菌。该菌种直到最近才被报道仅从眼表分离得到。麦氏棒状杆菌对眼科常用的局部抗生素普遍敏感。
结论
尽管麦氏棒状杆菌的致病性尚未确定，但该微生物应被视为细菌性二重感染的潜在病因。适当的抗生素治疗可使其清除并治愈结膜炎。
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本文引用的文献
1
Corynebacterium macginleyi has to date been isolated exclusively from conjunctival swabs.
J Clin Microbiol. 1998 Dec;36(12):3670-3. doi: 10.1128/JCM.36.12.3670-3673.1998.
2
Mycobacterium chelonei masquerading as Corynebacterium in a case of infectious keratitis: a diagnostic dilemma.
Cornea. 1998 Mar;17(2):230-2. doi: 10.1097/00003226-199803000-00021.
3
Clinical microbiology of coryneform bacteria.
Clin Microbiol Rev. 1997 Jan;10(1):125-59. doi: 10.1128/CMR.10.1.125.
4
Species identities and antimicrobial susceptibilities of corynebacteria isolated from various clinical sources.
Eur J Clin Microbiol Infect Dis. 1996 Aug;15(8):657-62. doi: 10.1007/BF01691153.
5
Corynebacterium minutissimum endophthalmitis: management with antibiotic irrigation of the capsular bag.
Int Ophthalmol. 1995;19(5):313-6. doi: 10.1007/BF00130928.
6
Acute conjunctivitis in childhood.
J Pediatr. 1993 Jan;122(1):10-4. doi: 10.1016/s0022-3476(05)83479-1.
7
Corynebacterium striatum: a diphtheroid with pathogenic potential.
Clin Infect Dis. 1993 Jul;17(1):21-5. doi: 10.1093/clinids/17.1.21.
8
[Normal flora of the human conjunctiva: examination of 135 persons of various ages].
Klin Monbl Augenheilkd. 1994 Dec;205(6):348-57. doi: 10.1055/s-2008-1045542.
9
Genomic diversity and phylogenetic relationships among lipid-requiring diphtheroids from humans and characterization of Corynebacterium macginleyi sp. nov.
Int J Syst Bacteriol. 1995 Jan;45(1):128-33. doi: 10.1099/00207713-45-1-128.
10
The lowly diphtheriod: nondiphtheria corynebacterial infections in humans.
West J Med. 1982 Jul;137(1):45-52.
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