Shechter M, Sharir M, Labrador M J, Forrester J, Merz C N
Department of Medicine, Cedars-Sinai Medical Center and the UCLA School of Medicine, Los Angeles, California 90048, USA.
Am J Cardiol. 2000 Dec 1;86(11):1256-9, A6. doi: 10.1016/s0002-9149(00)01214-5.
To determine whether the current National Cholesterol Education Program cholesterol recommendations are consistent with beneficial endothelium-dependent vasodilation, we prospectively assessed endothelium-dependent brachial artery vasoreactivity in 50 patients with stable coronary artery disease. Our results showed that endothelial-dependent vasoreactivity was greater when low-density lipoprotein cholesterol was <100 mg/dl, suggesting that it may be beneficial to reach the National Cholesterol Education Program Adult Treatment Panel II target of low-density lipoprotein cholesterol of <100 mg/dl.
为了确定当前国家胆固醇教育计划的胆固醇推荐标准是否与有益的内皮依赖性血管舒张作用相一致，我们前瞻性地评估了50例稳定型冠状动脉疾病患者的内皮依赖性肱动脉血管反应性。我们的结果显示，当低密度脂蛋白胆固醇<100mg/dl时，内皮依赖性血管反应性更强，这表明达到国家胆固醇教育计划成人治疗小组II设定的低密度脂蛋白胆固醇<100mg/dl的目标可能是有益的。
