Latini G
Division of Pediatrics, Ospedale A. Perrino, Brindisi, Italy.
Biol Neonate. 2000 Nov;78(4):269-76. doi: 10.1159/000014278.
Many plastic items are made of polyvinylchloride (PVC) blended with plasticizers. The most frequently used plasticizer is di-(2-ethylhexyl)-phthalate (DEHP). DEHP migrates at a constant rate from plastics to the environment: it has been detected in water, soil and food and is therefore considered as a widespread environmental contaminant. Over the past several years, a number of publications concerning toxic effects of DEHP on animals and humans have been reported. Although DEHP is suggested to be of low acute toxicity, long-term exposure, especially in human beings at risk such as pregnant women and children, requires more in-depth studies. If DEHP toxicity in humans were to be confirmed, it would be advisable in the future to replace current PVC plasticizers, especially if they come into contact with babies, with better-quality materials.
许多塑料制品由聚氯乙烯(PVC)与增塑剂混合制成。最常用的增塑剂是邻苯二甲酸二(2-乙基己基)酯(DEHP)。DEHP以恒定速率从塑料迁移到环境中:已在水、土壤和食物中检测到它,因此被视为一种广泛存在的环境污染物。在过去几年中,已有多篇关于DEHP对动物和人类毒性作用的报道。尽管DEHP被认为急性毒性较低,但长期接触,尤其是对孕妇和儿童等高危人群,需要更深入的研究。如果DEHP对人类的毒性得到证实,未来最好用质量更好的材料替代当前的PVC增塑剂,特别是当它们与婴儿接触时。