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科氏葡萄球菌——医院环境中的定植菌:细胞表面特征及抗生素耐药性

Staphylococcus cohnii--resident of hospital environment: cell-surface features and resistance to antibiotics.

作者信息

Szewczyk E M, Rózalska M

机构信息

Department of Pharmaceutical Microbiology, Medical University of Lódź, Poland.

出版信息

Acta Microbiol Pol. 2000;49(2):121-33.

Abstract

Staphylococcus cohnii strains dominated in the environment of investigated hospitals. We isolated 420 strains of the species mainly from hospitals environments, but also from infants--Intensive Care Units patients, its medical staff and non-hospital environments. S. cohnii subspecies cohnii was seen to dominate (361 strains). Seventy seven percent of these strains expressed cell-surface hydrofobicity, most of them were slime producers (61%) and this feature was correlated with their methicillin resistance. Among S. cohnii ssp. cohnii strains isolated from ICU environment 90% were resistant to methicillin, 43% expressed high-level resistance to mupirocin and high percentages were resistant to many other antibiotics. These strains may constitute a dangerous reservoir of resistance genes in a hospital.

摘要

科氏葡萄球菌菌株在所调查医院的环境中占主导地位。我们分离出了420株该菌种,主要来自医院环境,但也有来自婴儿重症监护病房的患者、医护人员以及非医院环境。科氏葡萄球菌科氏亚种占主导地位(361株)。这些菌株中有77%表现出细胞表面疏水性,其中大多数(61%)是黏液产生菌,并且这一特性与它们对甲氧西林的耐药性相关。在从重症监护病房环境分离出的科氏葡萄球菌科氏亚种菌株中,90%对甲氧西林耐药,43%对莫匹罗星表现出高水平耐药,并且有很高比例的菌株对许多其他抗生素耐药。这些菌株可能构成医院中耐药基因的危险储存库。

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