Ansari I, Chauhan B C, McCormick T A, LeBlanc R P
Departments of Ophthalmology and. Physiology and Biophysics, Dalhousie University, Halifax, Nova Scotia, Canada.
Invest Ophthalmol Vis Sci. 2000 Dec;41(13):4150-7.
To determine whether pattern discrimination perimetry detects progression of glaucomatous visual fields earlier than conventional static automated perimetry.
One hundred nine eyes of 109 patients with open angle glaucoma were enrolled in a longitudinal prospective study. Each patient underwent visual field examinations with conventional and pattern discrimination perimetry using the 30-2 program of the Humphrey Visual Field Analyzer (Humphrey Instruments Inc., San Leandro, CA) and a custom program for the pattern discrimination perimeter, respectively at 6-month intervals. Progression of glaucomatous visual field damage was assessed separately at each visit by predetermined criteria for conventional and pattern discrimination perimetry. The time to progression from baseline was calculated and the hemifield that showed progression first was documented for both conventional and pattern discrimination perimetry.
Patients were followed for a mean of 5.1 years and a mean of 11.6 visits. Sixty-eight (62.3%) patients did not show progression with either technique. Of the remaining 41 patients, 15 (36.5%) showed progression with conventional perimetry alone, 9 (21.9%) with pattern discrimination perimetry alone, and 17 (41.4%) showed progression with both techniques. Of these 17 patients, 11 (64.7%) were detected earlier by conventional perimetry, and 6 (35.2%) were detected earlier by pattern discrimination perimetry.
This study suggests that pattern discrimination perimetry is less effective than conventional perimetry in evaluating progressive glaucomatous visual field damage.
确定模式分辨视野检查法是否比传统的静态自动视野检查法能更早地检测出青光眼视野的进展。
109例开角型青光眼患者的109只眼睛纳入一项纵向前瞻性研究。每位患者分别每隔6个月使用Humphrey视野分析仪（Humphrey Instruments Inc.，加利福尼亚州圣莱安德罗）的30-2程序进行传统视野检查和模式分辨视野检查，并使用自定义程序进行模式分辨视野计检查。每次就诊时分别根据传统视野检查和模式分辨视野检查的预定标准评估青光眼视野损害的进展情况。计算从基线开始进展的时间，并记录传统视野检查和模式分辨视野检查中首先出现进展的半视野。
患者平均随访5.1年，平均就诊11.6次。68例（62.3%）患者两种检查方法均未显示进展。在其余41例患者中，15例（36.5%）仅传统视野检查显示进展，9例（21.9%）仅模式分辨视野检查显示进展，17例（41.4%）两种检查方法均显示进展。在这17例患者中，11例（64.7%）传统视野检查更早检测到进展，6例（35.2%）模式分辨视野检查更早检测到进展。
本研究提示，在评估青光眼进展性视野损害方面，模式分辨视野检查法不如传统视野检查法有效。
