Horenblas S, Kröger R, van Boven E, Meinhardt W, Newling D W
Department of Urology, Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.
Eur Urol. 2000 Nov;38(5):613-7. doi: 10.1159/000020340.
Urinary fistula after treatment for cancer constitutes a therapeutic dilemma, especially in patients who have had various other treatments. We report on 7 patients with urinary leakage, treated conservatively with ureteric occlusion by way of percutaneous transrenal balloon catheters.
The indication for ureteral occlusion was persisting urinary leakage despite diversion by nephrostomy and drainage with atransurethral catheter. All patients had had previous treatment because of pelvic malignancy. Small Foley balloon catheters and angioplasty catheters were used. These devices were inserted percutaneously in an antegrade fashion.
In all but 2 of the patients the leakage ceased with the aid of these devices. Insufficient ureteral occlusion necessitated unilateral uretero-cutaneostomy in 1 patient. In another patient a vesico vaginal fistula was closed surgically. The maximum duration of occlusion was 169 (mean 94, range 45-169) days, without any evidence of ureteric pressure necrosis. Despite good overall results many adjustments and replacements of catheters were necessary because of recurrent urinary leakage caused by inadequate obstruction and/or leakage of the occluding catheters.
We conclude that long-term ureteral occlusion with percutaneous transrenal balloon catheters appears to be safe and does not result in pressure necrosis. Using this approach, urinary fistula can heal in some patients without the need for open surgery.
癌症治疗后出现尿瘘是一个治疗难题,对于接受过多种其他治疗的患者尤其如此。我们报告7例尿漏患者,通过经皮经肾球囊导管进行输尿管封堵,采用保守治疗。
输尿管封堵的指征是尽管已通过肾造瘘引流和经尿道导管引流,但仍存在持续性尿漏。所有患者既往均因盆腔恶性肿瘤接受过治疗。使用了小号弗利导尿管和血管成形术导管。这些装置经皮顺行插入。
除2例患者外,其他患者借助这些装置后尿漏均停止。1例患者因输尿管封堵不足而行单侧输尿管皮肤造口术。另1例患者的膀胱阴道瘘通过手术闭合。封堵的最长持续时间为169天(平均94天,范围45 - 169天),未发现输尿管压力性坏死的证据。尽管总体效果良好,但由于封堵不足和/或封堵导管漏液导致反复尿漏,仍需要多次调整和更换导管。
我们得出结论,经皮经肾球囊导管进行长期输尿管封堵似乎是安全的,不会导致压力性坏死。采用这种方法,一些患者的尿瘘无需开放手术即可愈合。