Kaul V, Friedenberg F, Rothstein KD
Center for Liver Disease, Albert Einstein Medical Center, 5401 Old York Road, Klein Building, Suite 509, Philadelphia, PA 19141, USA.
Curr Treat Options Gastroenterol. 2000 Dec;3(6):439-444. doi: 10.1007/s11938-000-0031-x.
Treatment of hepatic cysts should be considered only for those patients who are symptomatic. For simple cysts, percutaneous aspiration invariably leads to recurrence; laparoscopic deroofing is usually curative. Open deroofing (fenestration) should be reserved for cysts inaccessible by laparoscopy. Percutaneous instillation of sclerosing agents (ethanol, iophendylate, minocycline) into nonbiliary and nonparasitic cysts is an alternative therapeutic option in certain cases. Due to increased morbidity, hepatic resection should be reserved for polycystic liver disease, diffuse hepatic involvement, or recurrence after a deroofing procedure. Patients with congenital fibropolycystic disorders (eg, congenital hepatic fibrosis) with evidence of hepatic decompensation, should be considered for liver transplantation. For hepatic hydatid cysts, simple cystectomy or the PAIR (puncture, aspirate, inject, and reaspirate) technique with albendazole treatment have been shown to be equally successful. In the case of alveolar echinococcosis, hepatic resection and liver transplantation are the only effective modalities for localized and extensive hepatic disease, respectively.
仅对有症状的患者考虑肝囊肿的治疗。对于单纯性囊肿,经皮穿刺抽吸总会导致复发;腹腔镜去顶术通常可治愈。开放性去顶术(开窗术)应保留用于腹腔镜无法到达的囊肿。在某些情况下,向非胆管性和非寄生性囊肿经皮注入硬化剂(乙醇、碘苯酯、米诺环素)是一种替代治疗选择。由于发病率增加,肝切除术应保留用于多囊肝病、弥漫性肝脏受累或去顶术后复发的情况。有先天性肝代偿失调证据的先天性纤维多囊性疾病(如先天性肝纤维化)患者,应考虑肝移植。对于肝包虫囊肿,单纯囊肿切除术或采用阿苯达唑治疗的PAIR(穿刺、抽吸、注入和再次抽吸)技术已被证明同样成功。对于泡型棘球蚴病,肝切除术和肝移植分别是局限性和广泛性肝脏疾病的唯一有效治疗方式。