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局部热敷与冰敷对眼肌型重症肌无力所致上睑下垂的影响。

Effect of local heat versus ice on blepharoptosis resulting from ocular myasthenia.

作者信息

Movaghar M, Slavin M L

机构信息

Division of Neuro-ophthalmology, Department of Ophthalmology, Long Island Jewish Medical Center, The Albert Einstein College of Medicine, Great Neck, New York, USA.

出版信息

Ophthalmology. 2000 Dec;107(12):2209-14. doi: 10.1016/s0161-6420(00)00465-6.

DOI:10.1016/s0161-6420(00)00465-6
PMID:11097597
Abstract

OBJECTIVE

To determine the effect of heat versus ice application to a ptotic eyelid in patients with ocular or systemic myasthenia.

DESIGN

Observational case series.

PARTICIPANTS

Three consecutive patients and one subsequent patient with ptosis and clinical or laboratory signs of myasthenia were initially evaluated.

METHODS

In all four patients, the heat test and the ice test were performed. In three patients, the modified sleep test was also performed. In the heat or ice test, the patient was asked to hold a heat or ice pack, respectively, over the closed ptotic eye for 10 to 15 minutes. The modified sleep test was performed by having the patient close both eyes for a 10- to 15-minute period. Photographs were taken before and immediately after each test.

MAIN OUTCOME MEASURE

The effect of heat or ice on ptosis.

RESULTS

Transient complete improvement of ptosis in three patients and marked improvement in one patient was noted after each test. The results of the heat, ice, and modified sleep tests were identical.

CONCLUSIONS

Marked improvement of myasthenic ptosis in all four patients occurred regardless of local warming or cooling. The common denominator of all these tests, rest, seems to be the relevant factor in the study as designed.

摘要

目的

确定热敷与冰敷对患有眼部或全身性重症肌无力患者上睑下垂的影响。

设计

观察性病例系列。

参与者

最初对3例连续患者和1例后续出现上睑下垂且有重症肌无力临床或实验室体征的患者进行了评估。

方法

对所有4例患者均进行了热敷试验和冰敷试验。对3例患者还进行了改良睡眠试验。在热敷或冰敷试验中,要求患者分别在闭合的下垂眼上放置热敷袋或冰敷袋10至15分钟。改良睡眠试验是让患者双眼闭合10至15分钟。在每次试验前和试验后立即拍照。

主要观察指标

热敷或冰敷对上睑下垂的影响。

结果

每次试验后,3例患者上睑下垂出现短暂完全改善,1例患者有明显改善。热敷、冰敷和改良睡眠试验的结果相同。

结论

无论局部温热或冷却,所有4例患者的重症肌无力性上睑下垂均有明显改善。在本研究设计中,所有这些试验的共同因素,即休息,似乎是相关因素。

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