Ng P W, Yeung B Y, Yick D W, Yu C B, Lam D S
Hospital Authority Ophthalmic Services, Hong Kong Eye Hospital, Kowloon, Hong Kong.
Ophthalmology. 2000 Dec;107(12):2310-3. doi: 10.1016/s0161-6420(00)00460-7.
To assess the safety and efficacy of fornix-based trabeculectomy with Wise's suture technique in Chinese subjects.
A retrospective noncomparative case series.
Forty-eight eyes of 44 Chinese subjects that underwent fornix-based trabeculectomy combined with intraoperative 0.4 mg/ml mitomycin-C for 3 to 5 minutes were studied.
Conjunctival wound closure of all eyes was with the Wise's technique using 9-0 nylon suture to prevent leakage at the corneolimbal interface.
The success rate, with or without antiglaucoma medication, the complication rate, and the longevity of the drainage blebs were analyzed.
At a mean follow-up period of 21.8 +/- 4.5 months, 75% (36 eyes) had postoperative intraocular pressure of 21 mmHg or less. Of these, 23 eyes (47.9%) required no antiglaucoma medication, 7 eyes (14.6%) required one medication, 3 eyes (6.3%) required two medications, and 3 eyes (6.3%) required three medications. Ten eyes (21%) had early wound leak. Two eyes (4.2%) required surgical repair. Two eyes (4%) had hypotonous maculopathy. No other major complications were encountered.
Fornix-based trabeculectomy with adjunctive mitomycin-C using Wise's suture technique appears to be both safe and effective in Chinese subjects.
评估采用怀斯缝合技术的穹窿部小梁切除术在中国受试者中的安全性和有效性。
一项回顾性非对照病例系列研究。
对44名中国受试者的48只眼睛进行了研究,这些眼睛接受了穹窿部小梁切除术,并在术中使用0.4毫克/毫升丝裂霉素C 3至5分钟。
所有眼睛的结膜伤口均采用怀斯技术,用9-0尼龙缝线缝合,以防止角膜缘界面渗漏。
分析了无论是否使用抗青光眼药物的成功率、并发症发生率以及引流泡的寿命。
平均随访21.8±4.5个月时,75%(36只眼)术后眼压≤21 mmHg。其中,23只眼(47.9%)无需使用抗青光眼药物,7只眼(14.6%)需要一种药物,3只眼(6.3%)需要两种药物,3只眼(6.3%)需要三种药物。10只眼(21%)发生早期伤口渗漏。2只眼(4.2%)需要手术修复。2只眼(4%)发生低眼压性黄斑病变。未遇到其他主要并发症。
采用怀斯缝合技术并辅助丝裂霉素C的穹窿部小梁切除术在中国受试者中似乎既安全又有效。