Häusler H J, Möckel A, Voppmann A, Schneider P
Klinik für Kinderkardiologie, Herzzentrum der Universität Leipzig.
Z Kardiol. 2000 Oct;89(10):906-13. doi: 10.1007/s003920070164.
Accurate and efficient echocardiographic on-line determination of left ventricular volume would be advantageous in the care of children with congenital heart disease and children with hemodynamic instability. The prospective study was performed to evaluate the clinical usefulness of the on-line automatic border detection system (acoustic quantification: AQ) for determination of left ventricular volumes and ejection fraction in comparison to the conventional off-line method (manual tracing). 107 patients were enrolled in the study. The ages ranged from 0.1 to 18.8 years (mean 8.3 +/- 5.6). All patients were studied in the apical four-chamber plane for acoustic quantification (AQ) and manual tracing as well. Left ventricular volumes were determined using the mono-plane Simpson's rule. Left ventricular end-diastolic volumes obtained by AQ correlated well but were slightly underestimated compared to those determined by manual tracing (r = 0.99). Left ventricular endsystolic volumes by AQ correlated well but were also slightly underestimated compared to those obtained by manual tracing (r = 0.98). Mean ejection fraction was 61.1 +/- 6.8% by AQ compared with 61.5 +/- 5.9% by manual tracing. Linear regression analysis demonstrated good correlation: y = 0.77x + 14.1, r = 0.89; p < 0.001. Measurement of left ventricular volumes and ejection fraction by AQ using automatic border detection compares well with measurements done by manual tracing. However, AQ tends to underestimate to some degree. The time necessary for acquisition of data was similar in both methods. AQ seems to be a promising method for real-time estimation of left ventricular volume, even in children.
准确而高效地超声心动图在线测定左心室容积，对于先天性心脏病患儿及血流动力学不稳定的患儿的治疗将大有裨益。本前瞻性研究旨在评估在线自动边界检测系统（声学定量：AQ）与传统离线方法（手动描记）相比，在测定左心室容积和射血分数方面的临床实用性。107例患者纳入本研究。年龄范围为0.1至18.8岁（平均8.3±5.6岁）。所有患者均在心尖四腔心切面进行声学定量（AQ）及手动描记研究。使用单平面辛普森法则测定左心室容积。AQ获得的左心室舒张末期容积相关性良好，但与手动描记法相比略有低估（r = 0.99）。AQ获得的左心室收缩末期容积相关性良好，但与手动描记法相比也略有低估（r = 0.98）。AQ测得的平均射血分数为61.1±6.8%，而手动描记法测得的为61.^5±5.9%。线性回归分析显示相关性良好：y = 0.77x + 14.1，r = 0.89；p < 0.001。使用自动边界检测的AQ测定左心室容积和射血分数与手动描记法的测量结果相当。然而，AQ在一定程度上有低估的倾向。两种方法采集数据所需时间相似。AQ似乎是一种用于实时估计左心室容积的有前景的方法，即使在儿童中也是如此。
