Hoshi E, Tanji J
Department of Physiology, Tohoku University School of Medicine, Sendai, Japan.
Nature. 2000 Nov 23;408(6811):466-70. doi: 10.1038/35044075.
To plan an action, we must first select an object to act on and the body part (or parts) to use to accomplish our intention. To plan the motor task of reaching, we specify both the target to reach for and the arm to use. In the process of planning and preparing a motor task, information about the motor target and the arm to use must be integrated before a motor program can be formulated to generate the appropriate limb movement. One of the structures in the brain that is probably involved in integrating these two sets of information is the premotor area in the cerebral cortex of primates. The lateral sector of the dorsal premotor cortex is known to receive both visual and somatosensory input, and we show here that neurons in this area gather information about both the target and the body part, while subsequent activity specifies the planned action.
为了计划一个动作，我们必须首先选择一个要作用的对象以及用于实现我们意图的身体部位。为了计划伸手抓取的运动任务，我们要明确抓取的目标以及使用的手臂。在计划和准备一个运动任务的过程中，关于运动目标和要使用的手臂的信息必须在制定运动程序以产生适当的肢体运动之前进行整合。大脑中可能参与整合这两组信息的结构之一是灵长类动物大脑皮层中的运动前区。已知背侧运动前皮层的外侧部分接收视觉和躯体感觉输入，并且我们在此表明该区域的神经元收集有关目标和身体部位的信息，而随后的活动则明确了计划的动作。
