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免疫功能低下患者毛霉病和曲霉属鼻-鼻窦炎的成功治疗

Successful Treatment of Mucormycosis and Aspergillus sp. Rhinosinusitis in an Immunocompromised Patient.

作者信息

Borges V, Medeiros S, Ziomkowski S, Machado A

机构信息

Infection Control Service, Clinical Hospital of Porto Alegre, Federal University of Rio Grande do Sul,Brazil.

出版信息

Braz J Infect Dis. 1998 Aug;2(4):209-211.

PMID:11103010
Abstract

Fungal rhinosinusitis is a serious infection related to immunosuppressive conditions. It is caused by common opportunistic mycoses, such as Mucor, Aspergillus sp. and Candida sp. Treatment is difficult and most of the patients with an invasive form, die. We report a case of a 13 year old boy who developed Mucor and Aspergillus sp rhinosinusitis while receiving chemotherapy for acute lymphoblastic leukemia. Even though the patient was intensely immunossupressed, early diagnoses associated with surgical debridement and effective doses of amphotericin B allowed a favorable outcome and hospital discharge.

摘要

真菌性鼻-鼻窦炎是一种与免疫抑制状态相关的严重感染。它由常见的机会性霉菌引起,如毛霉、曲霉菌属和念珠菌属。治疗困难,大多数侵袭性类型的患者会死亡。我们报告一例13岁男孩的病例,该男孩在接受急性淋巴细胞白血病化疗时发生了毛霉和曲霉菌属鼻-鼻窦炎。尽管患者处于严重免疫抑制状态,但早期诊断并结合手术清创和有效剂量的两性霉素B使患者获得了良好的预后并得以出院。

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