Dry S, McCarthy S, Harris T
Structural GenomiX Inc, San Diego, California 92121, USA.
Nat Struct Biol. 2000 Nov;7 Suppl:946-9. doi: 10.1038/80718.
Commercial efforts in structural genomics focus on providing to pharmaceutical customers information that relates to the suitability of specific proteins as drug targets and the informed selection and refinement of lead compounds generated by high-throughput screening and rational approaches. These efforts follow a variety of business models and are impacted by activities in the public domain, recent technological advances, and the changing intellectual property landscape.
结构基因组学的商业活动致力于为制药客户提供与特定蛋白质作为药物靶点的适用性相关的信息,以及通过高通量筛选和合理方法产生的先导化合物的明智选择和优化。这些活动遵循多种商业模式,并受到公共领域活动、近期技术进步和不断变化的知识产权格局的影响。