蛋白质生产：为晶体学家和核磁共振光谱学家提供支持。

Protein production: feeding the crystallographers and NMR spectroscopists.

作者信息

Edwards A M, Arrowsmith C H, Christendat D, Dharamsi A, Friesen J D, Greenblatt J F, Vedadi M

机构信息

Ontario Cancer Institute, Toronto, Canada.

出版信息

Nat Struct Biol. 2000 Nov;7 Suppl:970-2. doi: 10.1038/80751.

DOI:10.1038/80751

PMID:11104003

Abstract

Protein purification efforts for structural genomics will focus on automation for the readily-expressed proteins, and process development for the more difficult ones, such as membrane proteins. Thousands of proteins are expected to be produced in the next few years. The purified proteins will be valuable reagents for the entire research community.

摘要

用于结构基因组学的蛋白质纯化工作将聚焦于对易于表达的蛋白质进行自动化操作，以及对更具挑战性的蛋白质（如膜蛋白）开展工艺开发。预计在未来几年内将生产出数千种蛋白质。纯化后的蛋白质将成为整个研究界的宝贵试剂。