Józefowicz-Korczyńska M, Lukomski M
Katedry i Kliniki Otolaryngologii Akademii Medycznej w Lodzi.
Neurol Neurochir Pol. 2000 Jul-Aug;34(4):645-52.
The aim of the study was objective assessment of the results of betahistyne treatment in patients with chronic insufficiency of the vertebrobasilar artery system by means of elektronystagmography (ENG). The patients had mostly vertigo and/or dizziness, headache, ear buzzing and disequilibrium sensations. In 46 patients clinical, audiological and ENG examinations were carried out. All symptoms decreased in frequency after the treatment. Vertigo and/or dizziness improvement was noted in 58.5% patients of cases, headache decreased in 56.5% of cases, ear buzzing decreased in 42.8% and hearing improved in 22.2%. Before treatment 76% of patients had pathologic changes in ENG, after treatment improvement of ENG was noted in all tests, particularly in 17 cases (48.6%). This was most frequent in spontaneous nystagmus (83%), positional test (85%), caloric test (83%), and optokinetic test (71%). Comparison of complaints and ENG findings before and after treatment showed improvement both in symptoms and signs. Betaserc was effective in the treatment of patients with vertebrobasilar system insufficiency both in subjective opinions of patients and in objective assessment by ENG.