Zavras A I, Edelstein B L, Vamvakidis A
Department of Oral Health Policy and Epidemiology, Harvard School of Dental Medicine, Boston, MA 02115, USA.
J Public Health Dent. 2000 Summer;60(3):182-8. doi: 10.1111/j.1752-7325.2000.tb03325.x.
Modeling new biomedical technologies and determining their expected cost is necessary before initiating formal clinical trials. This paper estimates an economic model for the potential cost impact of microbiological screening of toddlers for caries risk compared to the traditional method of managing pediatric caries.
Potential cost savings were calculated based on screening test properties (sensitivity and specificity) derived from a population of 1,180 children aged 1 to 3 years with a caries prevalence of 15 percent. An algorithm was then developed to allocate prevalent and anticipate incident caries, treatment effectiveness assumptions, and existing regional treatment costs.
The cost analysis model conservatively predicts savings of 7.3 percent from screening and early intervention. Cumulative dental treatment costs for a child at age 4 years are $367.90 if the child has been screened and $396.70 otherwise. The model further predicts that cost savings increase significantly as caries prevalence increases.
Microbiologic risk assessment for pediatric caries may be an example of a preventive public health screening technique that results in both clinical benefits and cost savings. If the model is validated by randomized clinical trials, microbiologic screening could be used by pediatric primary care providers to identify toddlers who require early referral to dentists for further risk assessment and early caries management.
在启动正式临床试验之前,对新的生物医学技术进行建模并确定其预期成本是必要的。本文估计了一种经济模型,用于评估与传统的儿童龋齿管理方法相比,对幼儿进行龋齿风险微生物筛查的潜在成本影响。
根据从1180名1至3岁、龋齿患病率为15%的儿童群体中得出的筛查测试特性(敏感性和特异性)计算潜在成本节约。然后开发了一种算法,用于分配现患和预期的龋齿、治疗效果假设以及现有的区域治疗成本。
成本分析模型保守预测,筛查和早期干预可节省7.3%的成本。如果对儿童进行了筛查,4岁时的累积牙科治疗成本为367.90美元;否则为396.70美元。该模型还预测,随着龋齿患病率的增加,成本节约会显著增加。
儿童龋齿的微生物风险评估可能是一种预防性公共卫生筛查技术的实例,既能带来临床益处,又能节省成本。如果该模型通过随机临床试验得到验证,儿科初级保健提供者可使用微生物筛查来识别需要尽早转诊至牙医处进行进一步风险评估和早期龋齿管理的幼儿。