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[结直肠吻合口裂开:危险因素]

[The dehiscence of colorectal anastomoses: the risk factors].

作者信息

Testini M, Margari A, Amoruso M, Lissidini G, Bonomo G M

机构信息

Dipartimento per le Applicazioni in Chirurgia delle Tecnologie Innovative, Università degli Studi di Bari.

出版信息

Ann Ital Chir. 2000 Jul-Aug;71(4):433-40.

Abstract

OBJECTIVE

To evaluate the results of emergency and elective colorectal resective surgery; to identify general and local factors that influence the anastomotic leak rate.

MATERIAL AND METHOD

200 selected consecutive patients (115 males and 85 females, medium age 50.6 years, range 16-87) underwent resective colorectal surgery between 1990 to 1997. 154 (77.0%) were operated in elective surgery and 46 (23.0%) in urgency, for carcinoma, diverticular disease, mesenteric infarction, chronic intestinal disease, dolicosigma, anastomotic leakage, familiar polyposis or lesions by firearm. The operations consisted in 58 right colectomy, 28 left colectomy, 6 resection of the transverse and 29 of the sigmoid colon, 40 anterior resection, 12 total colectomy, 19 closing of colostomy, 6 by-passes. Anastomoses were performed in 88 cases by manual and in 110 by mechanical sutures.

RESULTS

We observed 12 (6%) anastomotic leakages. Mortality rate was 1.0%. 13%.0 of these patients were underwent before to emergency and 3.9% to elective surgery; 5.7% by manual and 6.4% by mechanical suture. Diagnosis of leakage was made by clinical features, blood vessel examinations and abdominal TC scan.

DISCUSSION

The risk factors of anastomotic leakage are general or local. Chronic obstructive pulmonary disease, perioperative transfusion, level of serum albumin, use of corticosteroid in the first group and sepsis, bowel obstruction, anastomotic level and tension and poor blood supply in the second, appear the most important causative factors in the development of anastomotic leaks.

CONCLUSION

The incidence of dehiscence in colo-rectal surgery was seen significatively lower when anastomoses were performed in ideal circumstances than in the presence of one or more unfavorable factors. Healing remains a process depending more on the patient than on any aspect of the surgical technique.

摘要

目的

评估急诊和择期结直肠切除手术的结果;确定影响吻合口漏发生率的全身和局部因素。

材料与方法

1990年至1997年间,连续选取200例患者(男性115例,女性85例,平均年龄50.6岁,范围16 - 87岁)接受结直肠切除手术。154例(77.0%)为择期手术,46例(23.0%)为急诊手术,病因包括癌症、憩室病、肠系膜梗死、慢性肠道疾病、乙状结肠冗长症、吻合口漏、家族性息肉病或火器伤。手术包括58例右半结肠切除术、28例左半结肠切除术、6例横结肠切除术、29例乙状结肠切除术、40例前切除术、12例全结肠切除术、19例结肠造口关闭术、6例旁路手术。88例采用手工吻合,110例采用机械缝合。

结果

我们观察到12例(6%)吻合口漏。死亡率为1.0%。这些患者中,13.0%为急诊手术前接受手术,3.9%为择期手术;手工缝合的为5.7%,机械缝合的为6.4%。通过临床特征、血管检查和腹部CT扫描诊断漏出情况。

讨论

吻合口漏的危险因素包括全身或局部因素。第一组中的慢性阻塞性肺疾病、围手术期输血、血清白蛋白水平、使用皮质类固醇,以及第二组中的败血症、肠梗阻、吻合部位和张力以及血供不良,似乎是吻合口漏发生的最重要致病因素。

结论

在理想情况下进行吻合时,结直肠手术中吻合口裂开的发生率明显低于存在一个或多个不利因素时。愈合仍然是一个更多取决于患者而非手术技术任何方面的过程。

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