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妊娠期间的暂时性肾小管酸中毒

Transient renal tubular acidosis in pregnancy.

作者信息

Seoud M, Adra A, Khalil A, Skaff R, Usta I, Salti I

机构信息

Department of Obstetrics & Gynecology, American University of Beirut Medical Center, Lebanon.

出版信息

Am J Perinatol. 2000;17(5):249-52. doi: 10.1055/s-2000-10006.

DOI:10.1055/s-2000-10006
PMID:11110342
Abstract

Renal tubular acidosis in pregnancy is a very rare disorder. Most cases are either inherited or secondary to maternal disease or ingestion of toxic chemicals. We report a 22-year-old woman, previously healthy, who presented at 27 weeks of gestation with preterm labor. Investigation revealed renal tubular acidosis with no obvious etiology. Labor was stopped with various tocolytic drugs and her electrolyte imbalance was corrected. She was delivered at 36 weeks, by cesarean for a nonreassuring fetal heart tracing, of an appropriate-for-gestational-age infant weighing 2905 g. Evaluation 3 and 6 months postpartum revealed gradual, but complete resolution of the acidosis and electrolyte abnormality. The infant is now 7 months old, is growing normally with normal electrolytes, and with no evidence of acidosis.

摘要

妊娠合并肾小管酸中毒是一种非常罕见的疾病。大多数病例为遗传性或继发于母体疾病或摄入有毒化学物质。我们报告一名22岁既往健康的女性,在妊娠27周时出现早产。检查发现肾小管酸中毒,病因不明。使用各种宫缩抑制剂停止了分娩,并纠正了她的电解质失衡。她在36周时因胎儿心率监护不良行剖宫产,分娩出一名体重2905g的适于胎龄儿。产后3个月和6个月的评估显示酸中毒和电解质异常逐渐但完全缓解。该婴儿现7个月大,生长正常,电解质正常,无酸中毒迹象。

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引用本文的文献

1
A Rare Case of Transient Proximal Renal Tubular Acidosis in Pregnancy.妊娠期罕见的短暂性近端肾小管酸中毒病例。
Case Rep Nephrol. 2017;2017:1342135. doi: 10.1155/2017/1342135. Epub 2017 Nov 29.
2
Renal tubular acidosis: an uncommon cause of bad obstetric history.肾小管酸中毒:不良产科病史的罕见原因。
J Obstet Gynaecol India. 2014 Dec;64(Suppl 1):34-5. doi: 10.1007/s13224-013-0440-0. Epub 2013 Aug 30.
3
Hypokalemic paraplegia in pregnancy.妊娠期低钾性截瘫
J Clin Diagn Res. 2014 Jun;8(6):OD03-4. doi: 10.7860/JCDR/2014/8793.4433. Epub 2014 Jun 20.