Machado M A, Stefani C M, Sallum E A, Sallum A W, Tramontina V A, Nogueira-Filho G R, Nociti Júnior F H
Department of Prosthesis and Periodontology, University of Campinas, Piracicaba SP, Brazil.
J Oral Sci. 2000 Sep;42(3):163-8. doi: 10.2334/josnusd.42.163.
The purpose of this study was to evaluate, by histometric analysis, re-osseointegration following treatment of ligature-induced peri-implantitis in dogs. Five dogs were used in this study. Their mandibular premolars (P2, P3 and P4) were first removed. After 3 additional months of healing, two titanium implants were placed on each side of the mandible. After 3 months, the abutment connection was performed and experimental peri-implantitis was induced by placing cotton ligatures in a submarginal position. Ligatures and abutments were removed after one month and the peri-implant bone defects were randomly assigned to one of the treatments: debridement, debridement plus guided-bone regeneration, debridement plus mineralized-bone graft, and debridement plus guided-bone regeneration associated with mineralized-bone graft. Five months post-treatment, the degree of bone contact with the implant surface and the bone area within the threads were measured in 12 threads, the 6 most coronal at each side of each implant. One-way analysis of variance did not reveal statistically significant differences between the treatment modalities (p > 0.05). Within the limits of the present study, it can be concluded that there is a limited possibility of re-osseointegration around implant surfaces previously exposed by ligature-induced peri-implantitis.
本研究的目的是通过组织计量学分析，评估犬结扎诱导性种植体周围炎治疗后的再骨结合情况。本研究使用了5只犬。首先拔除它们的下颌前磨牙（P2、P3和P4）。在额外愈合3个月后，在下颌两侧各植入两枚钛种植体。3个月后，进行基台连接，并通过在龈下位置放置棉线结扎诱导实验性种植体周围炎。1个月后移除结扎线和基台，将种植体周围骨缺损随机分配至以下一种治疗方式：清创、清创加引导骨再生、清创加矿化骨移植、清创加引导骨再生联合矿化骨移植。治疗后5个月，在每个种植体两侧最靠近牙冠的6个螺纹中，选取12个螺纹测量骨与种植体表面的接触程度以及螺纹内的骨面积。单因素方差分析未显示各治疗方式之间存在统计学显著差异（p>0.05）。在本研究的范围内，可以得出结论，在先前因结扎诱导性种植体周围炎而暴露的种植体表面周围，再骨结合的可能性有限。
