Ghirardini A, Nanni-Costa A, Venturi S, Ridolfi L, Petrini F, Taddei S, Venturoli A, Pugliese M R, Monti M, Martinelli G
Transplant Reference Center, Emilia-Romagna Region, Italy.
Transpl Int. 2000;13 Suppl 1:S267-71. doi: 10.1007/s001470050339.
The number of donations per million population (pmp) per year and the number of transplants pmp/year enables one to compare donation or transplant programs made in different years in the same area or made the same year in different areas. These pmp indexes may be integrated with an evaluation system by which each organ is evaluated separately in terms of the efficiency of its procurement and transplant systems using the procurement index (percentage in terms of number of organs utilized/number of organs procurable from donors utilized in a single area during 1 year) and the transplant index (percentage in terms of number of transplants performed/number of organs harvested in a single area during 1 year). We have called them Caldes I (procurement) and Caldes II (transplant) indexes. The harvest index evaluates the efficiency of utilization of organs retrieved from suitable donors. It usually ranges between 80-90% for the kidney, 70-95% for the liver, 40-50% for the heart, and 5-15% for the lungs. The transplant index evaluates for each organ the transplant team capacity to use available organs which can be harvested locally or in different areas. It usually ranges between 60-120%. Index determination did not require information different from the standard data available. Both the harvest and transplant indexes could be used to compare the efficiency of donation and transplant programs and policies in the same area during different years or at the same time in different areas. They can be critical in evaluating: (a) marginal donor utilization, (b) marginal organ utilization, and (c) dishomogeneity of organ retrieval and organ transplantation in different regions belonging to the same area. They also enable to evaluate if organs considered not available in a single area are offered to other areas or are not retrieved at all from available donors.
每年每百万人口(pmp)的捐赠数量以及每年每百万人口的移植数量,能够使人对同一地区不同年份或不同地区同一年开展的捐赠或移植项目进行比较。这些每百万人口指标可以与一个评估系统相结合,通过该系统,利用采购指数(一年内单个地区使用的器官数量占可从捐赠者获取的器官数量的百分比)和移植指数(一年内单个地区进行的移植数量占收获的器官数量的百分比),对每个器官的采购和移植系统效率分别进行评估。我们将它们称为卡尔德一世(采购)指数和卡尔德二世(移植)指数。收获指数评估从合适捐赠者获取的器官的利用效率。肾脏的收获指数通常在80% - 90%之间,肝脏为70% - 95%,心脏为40% - 50%,肺为5% - 15%。移植指数评估每个器官移植团队使用可在当地或不同地区收获的可用器官的能力。其通常在60% - 120%之间。指数的确定不需要与现有标准数据不同的信息。收获指数和移植指数均可用于比较不同年份同一地区或同一时间不同地区捐赠和移植项目及政策的效率。它们在评估以下方面可能至关重要:(a)边缘捐赠者的利用情况,(b)边缘器官的利用情况,以及(c)同一地区不同区域器官获取和器官移植的不均衡性。它们还能够评估单个地区认为不可用的器官是否提供给了其他地区,或者是否根本未从可用捐赠者处获取。