肌红蛋白在疑似急性冠脉综合征患者中的诊断及预后作用。北威州心肌梗死研究（NOWIS）组。
Diagnostic and prognostic role of myoglobin in patients with suspected acute coronary syndrome. North-Württemberg Infarction Study (NOWIS) Group.
作者信息
Störk T V, Wu A H, Müller-Bardorff M, Gareis R, Müller R, Hombach V, Katus H, Möckel M
机构信息
Department of Cardiology and Intensive Care, Karl-Olga Krankenhaus, Stuttgart, Germany.
出版信息
Am J Cardiol. 2000 Dec 15;86(12):1371-4, A5. doi: 10.1016/s0002-9149(00)01246-7.
In patients with suspected acute coronary syndrome, myoglobin is, according to IFCC and NACB guidelines, the marker of choice for early determination of acute infarction, in particular in combination with creatine kinase-MB, 4 hours after admission with a sensitivity of 96%, and correctly excludes Q-wave infarctions. In patients without acute myocardial infarction, a positive troponin T (relative risk 31.5%), but not an elevated myoglobin (relative risk 4.5%), is highly predictive for adverse in-hospital outcome.
根据国际临床化学和检验医学联合会（IFCC）及美国国家临床生物化学学会（NACB）的指南，对于疑似急性冠状动脉综合征的患者，肌红蛋白是早期判定急性梗死的首选标志物，尤其是与肌酸激酶-MB联合检测时，入院4小时后的敏感性为96%，且能正确排除Q波梗死。在无急性心肌梗死的患者中，肌钙蛋白T阳性（相对风险31.5%）而非肌红蛋白升高（相对风险4.5%）对院内不良结局具有高度预测性。
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