Gopal L, Sharma T, Shanmugam M, Badrinath S S, Sharma A, Agraharam S G, Choudhary A
Medical and Vision Research Foundation, Chennai, India.
Indian J Ophthalmol. 2000 Jun;48(2):101-6.
To describe our experience with management of eyes with stage 5 retinopathy of prematurity (ROP).
Closed vitreoretinal surgery was done on 96 eyes of patients with stage 5 ROP. Lens was sacrificed in all but one eye. Surgery involved an attempt to clear all preretinal tissue and open the peripheral trough all round. In most instances bimanual surgery under viscoelastic was performed.
At last follow up, anatomical success (defined as attached posterior pole) was achieved in 22.5% cases. Significant postoperative problems included reproliferation and secondary glaucoma. Only two infants obtained mobile vision.
Late identification of disease, lack of prior treatment such as laser or cryo, and higher incidence of narrow-narrow funnel configuration were responsible for the poor surgical results noted in this series. The poor surgical and functional results reemphasize the need for prompt screening and management of infants at risk.
描述我们对5期早产儿视网膜病变（ROP）眼部治疗的经验。
对96例5期ROP患者的眼睛进行了玻璃体视网膜闭合手术。除1只眼外，其余所有眼睛均摘除晶状体。手术试图清除所有视网膜前组织并全面打开周边视网膜下间隙。大多数情况下，在黏弹剂辅助下进行双手操作手术。
在最后一次随访时，22.5%的病例获得了解剖学成功（定义为后极部视网膜附着）。术后的显著问题包括再增殖和继发性青光眼。只有两名婴儿获得了可移动视力。
疾病发现较晚、缺乏激光或冷冻等前期治疗以及窄-窄漏斗型结构的高发生率导致了本系列中手术效果不佳。手术和功能效果不佳再次强调了对高危婴儿进行及时筛查和治疗的必要性。
