Cheng A T, Chen T H, Chen C C, Jenkins R
Division of Epidemiology, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Br J Psychiatry. 2000 Oct;177:360-5. doi: 10.1192/bjp.177.4.360.
Few studies of suicide have simultaneously examined the individual and combined effects of psychosocial and psychiatric risk factors.
To do so in a representative sample of suicides.
A case-control psychological autopsy was conducted among 113 consecutive suicides and 226 living controls matched for age, gender, ethnicity and area of residence in Taiwan.
Five major risk factors (loss event, suicidal behaviour in first-degree relatives, ICD-10 major depressive episode, emotionally unstable personality disorder and substance dependence) were found to have independent effects on suicide from multivariate conditional logistic regression analysis.
Effective intervention and management for loss event and major depressive episode among emotionally unstable subjects with a family tendency of suicidal behaviour, frequently also comorbid with alcohol or other substance dependence, may prove to be most effective for suicide prevention in different populations.
很少有关于自杀的研究同时考察心理社会和精神风险因素的个体及综合影响。
在具有代表性的自杀样本中进行此项研究。
对台湾地区113例连续自杀者及226名在年龄、性别、种族和居住地区相匹配的在世对照者进行病例对照心理解剖。
多变量条件逻辑回归分析发现,五个主要风险因素(丧失事件、一级亲属中有自杀行为、国际疾病分类第十版重度抑郁发作、情绪不稳定人格障碍和物质依赖)对自杀有独立影响。
对于有自杀行为家族倾向、常合并酒精或其他物质依赖的情绪不稳定个体,针对丧失事件和重度抑郁发作进行有效干预和管理,可能对不同人群预防自杀最为有效。