Brodin L A, Janerot-Sjöberg B
Funktionell bilddiagnostikutveckling, Huddinge Universitetssjukhus.
Lakartidningen. 2000 Nov 15;97(46):5302-4, 5307-9.
Echocardiography is presently a feasible method for quantitative estimation of intracardiac flows, pressure levels and for hemodynamic evaluation of valvular disease. The evaluation of regional myocardial function is still based on subjective scrutiny, and no routine method for the estimation of myocardial blood flow is available. We present an overview of newly developed techniques that are beginning to gain purchase in clinical practice. The use of native second harmonic imaging to improve image quality and of tissue Doppler to provide objective measurements of regional myocardial function is discussed. This article describes the transformation of tissue Doppler information into parametric images as in strain rate imaging, and overviews the use of ultrasound contrast agents. Used together with new imaging modalities, myocardial contrast echocardiography holds promise for future quantification of myocardial blood volume and flow. Other emerging echocardiographic technologies discussed are non-invasive measurement of coronary flow reserve and three dimensional cineloop visualization, developed to increase our understanding of cardiovascular physiological and anatomical coupling.
超声心动图目前是定量评估心内血流、压力水平以及评估瓣膜病血流动力学的一种可行方法。局部心肌功能的评估仍基于主观检查，且尚无估计心肌血流量的常规方法。我们概述了一些新开发的技术，这些技术已开始在临床实践中得到应用。讨论了使用自然二次谐波成像来改善图像质量以及使用组织多普勒来提供局部心肌功能的客观测量。本文描述了如应变率成像中将组织多普勒信息转化为参数图像的过程，并概述了超声造影剂的使用。心肌对比超声心动图与新的成像模式一起使用，有望在未来实现心肌血容量和血流的定量分析。讨论的其他新兴超声心动图技术包括无创测量冠状动脉血流储备以及三维电影环可视化，其开发目的是增进我们对心血管生理和解剖耦合的理解。
