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[饥饿对多布林贾人群血液蛋白质水平的影响(1992 - 1995年)]

[Effect of starvation on blood protein levels in the population of Dobrinja (1992-1995)].

作者信息

Hasković E

机构信息

Odsjek za biologiju, Prirodno-matematicki fakultet Univerziteta u Sarajevu.

出版信息

Med Arh. 2000;54(3):139-42.

PMID:11117008
Abstract

In nutritional protein deficiency, numerous studies verified utilization of amino acids generated from tissue degradation in intensive protein synthesis. Unlike liver, muscle protein synthesis is extremely dependent on external supplies of essential amino acids. Prolonged nutritional protein deficiency results in decrease of body weight as well as total protein concentration, in particular in early days of starvation. In prolonged starvation during the war, significant decrease of body weight was registered in 70 subjects while their total protein concentration remained within the expected range and did not significantly differ the values recorded in the control group. Concentration of serum albumines in the control group was lower than the concentration recorded in the tested group, while the serum globulins concentration was higher in the control group. Although the difference in body weight between the tested and the control group was statistically significant, no significant difference in the concentration of total proteins, albumines and globulines was recorded.

摘要

在营养性蛋白质缺乏的情况下,大量研究证实,在高强度蛋白质合成过程中,机体利用了组织降解产生的氨基酸。与肝脏不同,肌肉蛋白质合成极度依赖必需氨基酸的外部供应。长期营养性蛋白质缺乏会导致体重以及总蛋白浓度下降,尤其是在饥饿早期。在战争期间的长期饥饿状态下,70名受试者体重显著下降,而他们的总蛋白浓度仍在预期范围内,与对照组记录的值无显著差异。对照组血清白蛋白浓度低于试验组记录的浓度,而对照组血清球蛋白浓度更高。尽管试验组与对照组之间的体重差异具有统计学意义,但总蛋白、白蛋白和球蛋白浓度并无显著差异。

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