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墨西哥裔拉丁裔女性的围产期优势。

The perinatal advantage of Mexican-origin Latina women.

作者信息

Hessol N A, Fuentes-Afflick E

机构信息

Departments of Medicine, San Francisco, CA, USA.

出版信息

Ann Epidemiol. 2000 Nov;10(8):516-23. doi: 10.1016/s1047-2797(00)00073-9.

Abstract

PURPOSE

To determine if there is a perinatal advantage for birth outcomes among Mexican-origin Latina (Latina) women compared to white non-Hispanic (white) women, after adjusting for maternal, paternal, and infant factors.

METHODS

1,439,583 births from the 1990-1993 California linked birth and infant death certificate data sets were analyzed for the risk of low birth weight infants and infant mortality.

RESULTS

Latina women had a statistically higher unadjusted risk of low birth weight infants and infant mortality compared to white women. After adjusting for potential confounders, Latina women had a similar risk of low birth weight infants and a lower risk of infant mortality relative to white women. In multivariate analyses, the most significant risk factor for low infant birth weight was young gestational age (OR = 82.91 for gestational age 1-230 days and OR = 10.62 for gestational age 231-258 days) and the most significant risk factor for infant mortality was low birth weight (OR = 53.99 for infant birth weight <500 grams and OR = 9.27 for infant birth weight 500-2499 grams).

CONCLUSION

There was some evidence of a perinatal advantage for Latina women, when compared to white women and after adjusting for numerous potential confounders. To further reduce the risk of low birth weight infants and infant mortality, additional research is needed for etiologic clues beyond race/ethnicity and other traditional risk factors.

摘要

目的

在对母亲、父亲和婴儿因素进行调整之后,确定墨西哥裔拉丁裔女性相较于非西班牙裔白人女性在出生结局方面是否具有围产期优势。

方法

分析了1990 - 1993年加利福尼亚州出生与婴儿死亡证书关联数据集的1,439,583例出生数据,以研究低体重儿风险和婴儿死亡率。

结果

与白人女性相比,拉丁裔女性低体重儿和婴儿死亡率的未调整风险在统计学上更高。在对潜在混杂因素进行调整后,拉丁裔女性低体重儿风险与白人女性相似,婴儿死亡率风险则低于白人女性。在多变量分析中,婴儿低出生体重最显著的风险因素是孕周小(孕1 - 230天的比值比为82.91,孕231 - 258天的比值比为10.62),婴儿死亡最显著的风险因素是低出生体重(出生体重<500克的婴儿比值比为53.99,出生体重500 - 2499克的婴儿比值比为9.27)。

结论

有证据表明,在对众多潜在混杂因素进行调整后,拉丁裔女性与白人女性相比具有一定的围产期优势。为进一步降低低体重儿风险和婴儿死亡率,需要针对种族/族裔及其他传统风险因素之外的病因线索开展更多研究。

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