McLaren C J, Simpson E T
Department of Medical Imaging and Paediatric Surgery, The Canberra Hospital, ACT, Australia.
BJU Int. 2001 Jan;87(1):93-7. doi: 10.1046/j.1464-410x.2001.00997.x.
To determine the sensitivity of the direct radionuclide cystogram (DRC) in detecting vesico-ureteric reflux compared with the micturating cysto-urethrogram (MCU) in the same initial setting, in infants younger than one year.
The results from the dual cystograms of 62 refluxing infants < 1 year old (mean 0.58) were compared. Results from same-day renal scintigraphy with dimercaptosuccinic acid (DMSA) in 60 of the 62 infants were also compared with the reflux grades.
Reflux was detected in 105 units, 96 detected on the DRC and 47 on the MCU, representing a sensitivity of 91% and 45%, respectively. The DRC missed half of grade 1, 20% of grade 2 and 6% of grade 3 reflux. Reflux at low bladder filling rates (DRC) represented 40% of all reflux units, and a half (52%) of scarred renal units detected by DMSA scintigraphy.
In young infants the MCU may fail to detect significant reflux and the DRC may fail to detect the lesser grades. The combination of both cystograms in the initial investigation of reflux provides more comprehensive information.
在一岁以下婴儿中，与排尿性膀胱尿道造影（MCU）在相同初始条件下相比，确定直接放射性核素膀胱造影（DRC）检测膀胱输尿管反流的敏感性。
比较了62名年龄小于1岁（平均0.58岁）的反流婴儿的双重膀胱造影结果。还比较了62名婴儿中60名在同日进行的二巯基丁二酸（DMSA）肾闪烁显像结果与反流分级。
共检测到105个单位的反流，其中96个在DRC上检测到，47个在MCU上检测到，敏感性分别为91%和45%。DRC漏诊了一半的1级反流、20%的2级反流和6%的3级反流。低膀胱充盈率时的反流（DRC）占所有反流单位的40%，占DMSA闪烁显像检测到的瘢痕肾单位的一半（52%）。
在幼儿中，MCU可能无法检测到明显的反流，而DRC可能无法检测到较轻的分级。在反流的初始检查中，两种膀胱造影相结合可提供更全面的信息。
