Sherlock G, Hernandez-Boussard T, Kasarskis A, Binkley G, Matese J C, Dwight S S, Kaloper M, Weng S, Jin H, Ball C A, Eisen M B, Spellman P T, Brown P O, Botstein D, Cherry J M
Department of Genetics, Center for Clinical Sciences Research, 269 Campus Drive, Room 2255b, Stanford University, Stanford, CA 94305-5163, USA.
Nucleic Acids Res. 2001 Jan 1;29(1):152-5. doi: 10.1093/nar/29.1.152.
The Stanford Microarray Database (SMD) stores raw and normalized data from microarray experiments, and provides web interfaces for researchers to retrieve, analyze and visualize their data. The two immediate goals for SMD are to serve as a storage site for microarray data from ongoing research at Stanford University, and to facilitate the public dissemination of that data once published, or released by the researcher. Of paramount importance is the connection of microarray data with the biological data that pertains to the DNA deposited on the microarray (genes, clones etc.). SMD makes use of many public resources to connect expression information to the relevant biology, including SGD [Ball,C.A., Dolinski,K., Dwight,S.S., Harris,M.A., Issel-Tarver,L., Kasarskis,A., Scafe,C.R., Sherlock,G., Binkley,G., Jin,H. et al. (2000) Nucleic Acids Res., 28, 77-80], YPD and WormPD [Costanzo,M.C., Hogan,J.D., Cusick,M.E., Davis,B.P., Fancher,A.M., Hodges,P.E., Kondu,P., Lengieza,C., Lew-Smith,J.E., Lingner,C. et al. (2000) Nucleic Acids Res., 28, 73-76], Unigene [Wheeler,D.L., Chappey,C., Lash,A.E., Leipe,D.D., Madden,T.L., Schuler,G.D., Tatusova,T.A. and Rapp,B.A. (2000) Nucleic Acids Res., 28, 10-14], dbEST [Boguski,M.S., Lowe,T.M. and Tolstoshev,C.M. (1993) Nature Genet., 4, 332-333] and SWISS-PROT [Bairoch,A. and Apweiler,R. (2000) Nucleic Acids Res., 28, 45-48] and can be accessed at http://genome-www.stanford.edu/microarray.
斯坦福微阵列数据库(SMD)存储微阵列实验的原始数据和标准化数据,并为研究人员提供网络接口,以便他们检索、分析和可视化自己的数据。SMD的两个近期目标是作为斯坦福大学正在进行的研究中的微阵列数据的存储站点,并在数据一旦发表或由研究人员发布后促进其公开传播。至关重要的是将微阵列数据与与沉积在微阵列上的DNA(基因、克隆等)相关的生物学数据联系起来。SMD利用许多公共资源将表达信息与相关生物学联系起来,包括SGD [Ball,C.A., Dolinski,K., Dwight,S.S., Harris,M.A., Issel-Tarver,L., Kasarskis,A., Scafe,C.R., Sherlock,G., Binkley,G., Jin,H.等人(2000年)《核酸研究》,28卷,77 - 80页]、YPD和WormPD [Costanzo,M.C., Hogan,J.D., Cusick,M.E., Davis,B.P., Fancher,A.M., Hodges,P.E., Kondu,P., Lengieza,C., Lew-Smith,J.E., Lingner,C.等人(2000年)《核酸研究》,28卷,73 - 76页]、Unigene [Wheeler,D.L., Chappey,C., Lash,A.E., Leipe,D.D., Madden,T.L., Schuler,G.D., Tatusova,T.A.和Rapp,B.A.(2000年)《核酸研究》,28卷,10 - 14页]、dbEST [Boguski,M.S., Lowe,T.M.和Tolstoshev,C.M.(1993年)《自然遗传学》,4卷,332 - 333页]以及SWISS - PROT [Bairoch,A.和Apweiler,R.(2000年)《核酸研究》,28卷,45 - 48页],可通过http://genome - www.stanford.edu/microarray访问。