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斯坦福微阵列数据库支持其他微阵列平台和数据格式。

The Stanford Microarray Database accommodates additional microarray platforms and data formats.

作者信息

Ball Catherine A, Awad Ihab A B, Demeter Janos, Gollub Jeremy, Hebert Joan M, Hernandez-Boussard Tina, Jin Heng, Matese John C, Nitzberg Michael, Wymore Farrell, Zachariah Zachariah K, Brown Patrick O, Sherlock Gavin

机构信息

Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA.

出版信息

Nucleic Acids Res. 2005 Jan 1;33(Database issue):D580-2. doi: 10.1093/nar/gki006.

Abstract

The Stanford Microarray Database (SMD) (http://smd.stanford.edu) is a research tool for hundreds of Stanford researchers and their collaborators. In addition, SMD functions as a resource for the entire biological research community by providing unrestricted access to microarray data published by SMD users and by disseminating its source code. In addition to storing GenePix (Axon Instruments) and ScanAlyze output from spotted microarrays, SMD has recently added the ability to store, retrieve, display and analyze the complete raw data produced by several additional microarray platforms and image analysis software packages, so that we can also now accept data from Affymetrix GeneChips (MAS5/GCOS or dChip), Agilent Catalog or Custom arrays (using Agilent's Feature Extraction software) or data created by SpotReader (Niles Scientific). We have implemented software that allows us to accept MAGE-ML documents from array manufacturers and to submit MIAME-compliant data in MAGE-ML format directly to ArrayExpress and GEO, greatly increasing the ease with which data from SMD can be published adhering to accepted standards and also increasing the accessibility of published microarray data to the general public. We have introduced a new tool to facilitate data sharing among our users, so that datasets can be shared during, before or after the completion of data analysis. The latest version of the source code for the complete database package was released in November 2004 (http://smd.stanford.edu/download/), allowing researchers around the world to deploy their own installations of SMD.

摘要

斯坦福微阵列数据库(SMD)(http://smd.stanford.edu)是供数百名斯坦福大学研究人员及其合作者使用的研究工具。此外,SMD还为整个生物学研究界提供资源,它免费提供SMD用户发布的微阵列数据,并传播其源代码。除了存储点阵微阵列的GenePix(Axon Instruments公司)和ScanAlyze输出结果外,SMD最近还增加了存储、检索、显示和分析其他几种微阵列平台及图像分析软件包所产生的完整原始数据的功能,这样我们现在也能够接受来自Affymetrix GeneChips(MAS5/GCOS或dChip)、安捷伦目录阵列或定制阵列(使用安捷伦的特征提取软件)的数据,或者由SpotReader(Niles Scientific公司)生成的数据。我们已经实现了相关软件,使我们能够接受来自阵列制造商的MAGE-ML文档,并以MAGE-ML格式直接向ArrayExpress和GEO提交符合MIAME标准的数据,这大大提高了按照公认标准发布SMD数据的便捷性,同时也提高了已发布微阵列数据对普通公众的可获取性。我们引入了一种新工具来促进用户之间的数据共享,以便数据集能够在数据分析过程中、之前或之后进行共享。完整数据库包的最新版本源代码于2004年11月发布(http://smd.stanford.edu/download/),使世界各地的研究人员能够部署他们自己的SMD装置。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15b5/539960/1436fcd62942/gki006f1.jpg

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