Huvos A G, Marcove R C
J Bone Joint Surg Am. 1975 Mar;57(2):148-54.
Adamantinoma of long bones is a rare primary bone tumor. Approximately 100 cases have been reported in the literature. In the fourteen cases we studied in detail the ages of the patients ranged from thirteen to sixty-seven years and there were as many males as females. Twelve of the lesions were located in the tibia and two, in the humerus. The roentgenographic findings were sharply defined eccentric lobular lesions in the diaphysis. Some of the lesions were lytic and coarsely trabecular with a honeycomb appearance occasionally associated with periosteal new-bone formation. A sawtooth area of cortical-bone loss was found to be characteristic of this lesion. A microscopic finding is presented to support the theory of angioblastic origin of this tumor. The most successful treatment was amputation. Less often en bloc excision succeeded. Metastases to other bones, regional lymph nodes, and the lung were recorded.
长骨造釉细胞瘤是一种罕见的原发性骨肿瘤。文献报道约100例。在我们详细研究的14例中，患者年龄为13至67岁，男女数量相等。12处病变位于胫骨，2处位于肱骨。X线表现为骨干内边界清晰的偏心分叶状病变。部分病变呈溶骨性，小梁粗大，呈蜂窝状，偶尔伴有骨膜新生骨形成。皮质骨呈锯齿状缺失区是该病变的特征。本文提出了一项显微镜检查结果以支持该肿瘤起源于成血管细胞的理论。最成功的治疗方法是截肢。整块切除成功的情况较少。有转移至其他骨骼、区域淋巴结及肺部的记录。
