汉考克生物瓣膜在二尖瓣位置初次植入24年后出现功能故障。
Malfunction of a Hancock bioprosthesis in the mitral position 24 years after initial implantation.
作者信息
Niinami H, Naito Y, Koyanagi H, Nagashima H, Kasanuki H
机构信息
Department of Cardiovascular Surgery, The Heart Institute of Japan, Tokyo Women's Medical University.
出版信息
J Heart Valve Dis. 2000 Nov;9(6):810-2.
BACKGROUND AND AIMS OF THE STUDY
Although many types of cardiac bioprosthetic valves are currently available, the major disadvantage of their use is limited durability due to progressive structural valve deterioration. Few such valves function beyond 20 years.
METHODS
A 61-year-old man was admitted urgently to our institute with acute mitral insufficiency, 24 years after undergoing mitral valve replacement with a 25-mm standard Hancock porcine bioprosthesis for mitral stenosis.
RESULTS
Mitral valve reoperation was performed successfully with a mechanical valve. The explanted bioprosthesis showed leaflet perforations and a commissural tear, moderate calcification on the commissures, and pannus overgrowth.
CONCLUSION
The findings in this case suggest that individual patient variables, as well as the design and the construction of the valve are major determining factors in the rate of valve failure.
研究背景与目的
尽管目前有多种类型的心脏生物瓣膜可供使用，但其使用的主要缺点是由于瓣膜结构逐渐退化导致耐久性有限。很少有此类瓣膜能使用超过20年。
方法
一名61岁男性因急性二尖瓣关闭不全紧急入住我院，24年前他因二尖瓣狭窄接受了25毫米标准汉考克猪生物瓣膜二尖瓣置换术。
结果
成功使用机械瓣膜进行了二尖瓣再次手术。取出的生物瓣膜显示瓣叶穿孔、瓣叶联合处撕裂、瓣叶联合处中度钙化以及血管翳过度生长。
结论
该病例的研究结果表明，个体患者变量以及瓣膜的设计和结构是瓣膜失效发生率的主要决定因素。
Zotero 插件