Valenzuela M T, O'Ryan M
Departamento de Pediatría, Facultad de Medicina Oriente, Universidad de Chile.
Rev Med Chil. 2000 Aug;128(8):911-22.
The Expanded Program on Immunization (EPI) was initiated in 1974 in The Americas, based on the WHA 2757 resolution passed by the World Assembly of Health. Its purpose was to improve immunization coverage and to decrease morbidity and mortality caused by vaccine preventable diseases through vaccination. Specific goals were to eradicate in determined time periods poliomyelitis, measles, neonatal tetanus, to eliminate tuberculous meningitis in children four years and younger, diphtheria, and tetanus. This article presents up to date information on vaccination coverage trends between 1990 and 1998 in 13 countries of the American Region, briefly describes implementation of surveillance programs required for appropriate monitoring of vaccine impact, and discusses the changes observed in morbidity attributable to vaccine preventable disease in these countries during four periods, 1968 before the existence of EPI, 1978, four years after its introduction, 1988 and 1998. Although much remains to be done, the impact of EPI in the Americas has been outstanding in decreasing morbidity caused by vaccine preventable diseases.
扩大免疫规划(EPI)于1974年在美洲发起,其依据是世界卫生大会通过的第2757号决议。其目的是通过接种疫苗提高免疫接种覆盖率,并降低疫苗可预防疾病导致的发病率和死亡率。具体目标是在规定时间段内根除脊髓灰质炎、麻疹、新生儿破伤风,消除4岁及以下儿童的结核性脑膜炎、白喉和破伤风。本文介绍了美洲区域13个国家1990年至1998年期间疫苗接种覆盖率趋势的最新信息,简要描述了适当监测疫苗影响所需的监测计划的实施情况,并讨论了在四个时期(扩大免疫规划实施前的1968年、实施四年后的1978年、1988年和1998年)这些国家中疫苗可预防疾病所致发病率的变化情况。尽管仍有许多工作要做,但扩大免疫规划在美洲对降低疫苗可预防疾病所致发病率的影响十分显著。