单纯性及共病广泛性焦虑症的流行病学：近期研究综述与评估
The epidemiology of pure and comorbid generalized anxiety disorder: a review and evaluation of recent research.
作者信息
Kessler R C
机构信息
Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA.
出版信息
Acta Psychiatr Scand Suppl. 2000(406):7-13.
OBJECTIVE
Research documenting high rates of comorbidity among patients with generalized anxiety disorder (GAD) has led to the suggestion that GAD might best be conceptualized as a prodrome, residual or severity marker of other disorders. Recent research investigating this suggestion is reviewed in this report.
METHOD
A computer search cross-classified the terms 'Generalized Anxiety' and 'Comorbidity'.
RESULTS
Results arguing that GAD is an independent disorder include the finding that GAD is usually temporally primary in cases of comorbidity with major depression, that primary GAD is a significant predictor of subsequent depression and that the course of GAD is independent of comorbidity. Studies in both patient and community samples show that the impairment associated with pure GAD is equivalent to the impairment associated with pure depression.
CONCLUSION
The results reviewed here support the view that GAD as an independent disorder is a major public health problem.
目的
有研究记录广泛性焦虑症（GAD）患者中高共病率，这使得有人提出，GAD 最好被视为其他疾病的前驱症状、残留症状或严重程度标志物。本报告对近期调查这一观点的研究进行了综述。
方法
通过计算机检索对“广泛性焦虑”和“共病”这两个术语进行交叉分类。
结果
认为 GAD 是一种独立疾病的研究结果包括，在与重度抑郁症共病的案例中，GAD 通常在时间上是原发性的；原发性 GAD 是后续抑郁症的重要预测指标；GAD 的病程与共病无关。患者样本和社区样本的研究均表明，单纯 GAD 相关的损害与单纯抑郁症相关的损害相当。
结论
此处综述的结果支持以下观点，即作为一种独立疾病的 GAD 是一个重大的公共卫生问题。
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