Mathersul Danielle C, Rosenbaum Simon
War Related Illness and Injury Study Center, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304, USA; School of Medicine, Stanford University, Stanford, CA 94305, USA; Department of Psychology, University of Pennsylvania, Philadelphia, PA 19104, USA.
School of Psychiatry, Faculty of Medicine, University of New South Wales, Sydney, NSW 2052, Australia; The Black Dog Institute, Prince of Wales Hospital, University of New South Wales, Randwick, NSW, Australia.
Evid Based Complement Alternat Med. 2016;2016:4612953. doi: 10.1155/2016/4612953. Epub 2016 Dec 1.
Currently, there are no effective pharmaceutical treatments to reduce cognitive decline or prevent dementia. At the same time, the global population is aging, and rates of dementia and mild cognitive impairment (MCI) are on the rise. As such, there is an increasing interest in complementary and alternative interventions to treat or reduce the risk of cognitive decline. Depression is one potentially modifiable risk factor for cognitive decline and dementia. Notably, exercise and yoga are two interventions known to both reduce symptoms of depression and improve cognitive function. The current review discusses the efficacy of exercise and yoga to ameliorate depression and thereby reduce the risk of cognitive decline and potentially prevent dementia. Potential mechanisms of change, treatment implications, and future directions are discussed.
目前，尚无有效的药物治疗方法来减少认知衰退或预防痴呆症。与此同时，全球人口正在老龄化，痴呆症和轻度认知障碍（MCI）的发病率正在上升。因此，人们对用于治疗或降低认知衰退风险的补充和替代干预措施的兴趣与日俱增。抑郁症是认知衰退和痴呆症一个潜在的可改变风险因素。值得注意的是，运动和瑜伽是已知的两种既能减轻抑郁症状又能改善认知功能的干预措施。本综述讨论了运动和瑜伽改善抑郁从而降低认知衰退风险并潜在预防痴呆症的疗效。还讨论了潜在的变化机制、治疗意义和未来方向。
