Philip A G
J Pediatr. 1975 Mar;86(3):417-9. doi: 10.1016/s0022-3476(75)80976-0.
Size of the anterior fontanel and ossification of the epiphyseal centers at the knee were measured in 13 "discordant" twin pairs. There was a highly significant (p smaller than 0.01) negative correlation between fontanel size and epiphyseal ossification. Severe intrauterine growth retardation (demonstrated by the lighter twin) may result in retardation of membranous as well as enchondral ossification.
对13对“不一致”的双胞胎进行了前囟大小和膝关节骨骺中心骨化情况的测量。前囟大小与骨骺骨化之间存在高度显著的负相关（p小于0.01）。严重的宫内生长迟缓（较轻的双胞胎表现出）可能导致膜内成骨和软骨内成骨的迟缓。
