Failure to detect chromosome damage in vivo in Friend virus-infected leukemic mice.
作者信息
Majumdar S K, Bilenker J D
出版信息
J Natl Cancer Inst. 1975 Feb;54(2):503-5.
PMID:1113331
Abstract
The cytogenetic activity of Friend virus (FV) was tested in vivo on spleen and bone marrow cells of FV-infected leukemic C3H/HeJ and STS mice. No specific chromosome rearrangements were detected in the infected animals. Some chromosome abnormalities were recorded in both normal and diseased animals; however, aberrations did not significantly increase in the leukemic groups.
摘要
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